Home Neuronal Signaling Dopamine Receptor agonist - 5-HT Receptor agonist Rotigotine Hydrochloride For research use only.

Rotigotine Hydrochloride

Synonyms: N-0923 Hydrochloride

Rotigotine Hydrochloride (N-0923 Hydrochloride) is a potent Agonist of dopamine receptor, with Ki values of 0.71 nM for dopamine D3 receptor, 4-15 nM for D2, D5, D4 receptors, and 83 nM for dopamine D1 receptor. It also acts as a partial agonist of the 5-HT1A receptor, and as an antagonist of the α2B-adrenergic receptor.

Rotigotine Hydrochloride Chemical Structure

Rotigotine Hydrochloride Chemical Structure

CAS No. 125572-93-2

Purity & Quality Control

Batch: E485601 DMSO]70 mg/mL]false]Ethanol]4 mg/mL]false]Water]3 mg/mL]false Purity: 99.49%
99.49

Rotigotine Hydrochloride Related Products

Signaling Pathway

Dopamine Receptor Signaling Pathways

Dopamine Receptor Signaling Pathway

Biological Activity

Description Rotigotine Hydrochloride (N-0923 Hydrochloride) is a potent Agonist of dopamine receptor, with Ki values of 0.71 nM for dopamine D3 receptor, 4-15 nM for D2, D5, D4 receptors, and 83 nM for dopamine D1 receptor. It also acts as a partial agonist of the 5-HT1A receptor, and as an antagonist of the α2B-adrenergic receptor.

Chemical Information & Solubility

Molecular Weight 351.94 Formula

C19H25NOS.ClH
CAS No. 125572-93-2 SDF Download Rotigotine Hydrochloride SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 70 mg/mL ( (198.89 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 4 mg/mL

Water : 3 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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