Home Metabolism phosphatase inhibitor - DNA/RNA Synthesis inhibitor - CDK inhibitor Menadione bisulfite sodium For research use only.

Menadione bisulfite sodium

Synonyms: Menadione sodium bisulfite, Vitamin K3 sodium bisulfite

Menadione(Vitamin K3) bisulfite sodium, a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.

Menadione bisulfite sodium Chemical Structure

Menadione bisulfite sodium Chemical Structure

CAS No. 130-37-0

Purity & Quality Control

Batch: S595301 DMSO]55 mg/mL]false]Water]55 mg/mL]false]Ethanol]Insoluble]false Purity: 99.92%
99.92

Menadione bisulfite sodium Related Products

Biological Activity

Description Menadione(Vitamin K3) bisulfite sodium, a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.
Targets
Cdc25 phosphatase [1] pol γ [2]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01094444 Completed
Folliculitis
Per Pfeiffer|Odense University Hospital
 May 2010 Phase 2
NCT00656786 Completed
EGFR Inhibitor-associated Rash
Spectrum Pharmaceuticals Inc
 April 3 2008 Phase 1

Chemical Information & Solubility

Molecular Weight 276.24 Formula

C11H9NaO5S
CAS No. 130-37-0 SDF --
Smiles [Na+].CC1(CC(=O)C2=CC=CC=C2C1=O)[S]([O-])(=O)=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 55 mg/mL ( (199.1 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 55 mg/mL

Ethanol : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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