Home Metabolism phosphatase inhibitor PTP Inhibitor II For research use only.

PTP Inhibitor II

Synonyms: NSC 129010, 4-(Bromoacetyl)anisole

PTP Inhibitor II (NSC 129010, 4-(Bromoacetyl)anisole) is a cell-permeable protein tyrosine phosphatase (PTP) inhibitor that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with Ki value of 128 μM.

PTP Inhibitor II Chemical Structure

PTP Inhibitor II Chemical Structure

CAS No. 2632-13-5

Purity & Quality Control

Batch: S367801 DMSO]45 mg/mL]false]Ethanol]45 mg/mL]false]Water]Insoluble]false Purity: 99.56%
99.56

PTP Inhibitor II Related Products

Biological Activity

Description PTP Inhibitor II (NSC 129010, 4-(Bromoacetyl)anisole) is a cell-permeable protein tyrosine phosphatase (PTP) inhibitor that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with Ki value of 128 μM.
Targets
SHP-1(ΔSH2) [1]
(Cell-free)
128 μM(Ki)

Chemical Information & Solubility

Molecular Weight 229.07 Formula

C9H9BrO2
CAS No. 2632-13-5 SDF Download PTP Inhibitor II SDF
Smiles COC1=CC=C(C=C1)C(=O)CBr
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 45 mg/mL ( (196.44 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 45 mg/mL

Water : Insoluble


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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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