PTP Inhibitor II

Catalog No.S3678 Batch:S367801

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Technical Data

Formula

C9H9BrO2

Molecular Weight 229.07 CAS No. 2632-13-5
Solubility (25°C)* In vitro DMSO 45 mg/mL (196.44 mM)
Ethanol 45 mg/mL (196.44 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description PTP Inhibitor II (NSC 129010, 4-(Bromoacetyl)anisole) is a cell-permeable protein tyrosine phosphatase (PTP) inhibitor that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with Ki value of 128 μM.
Targets
SHP-1(ΔSH2) [1]
(Cell-free)
128 μM(Ki)

Protocol (from reference)

Selleck's PTP Inhibitor II has been cited by 1 publication

SHP1 tyrosine phosphatase gets involved in host defense against Streptococcus agalactiae infection and BCR signaling pathway in Nile tilapia (Oreochromis niloticus). [ Fish Shellfish Immunol, 2020, 99:562-571] PubMed: 32109611

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.