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Lithium carbonate

Name: Lithium carbonate
Brand: Selleck Chemicals
SKU: S4933
Rating: 5 (1 reviews)

Synonyms: Li2CO3

Catalog No.S4933 Purity:98%

Lithium carbonate (Li2CO3) is an inorganic compound that is valuable and effective agent in the treatment and prophylaxis of mood disorders, particularly bipolar disorder (BD). Lithium carbonate is able to alter D2 dopamine receptors response.

Lithium carbonate Chemical Structure

CAS No. 554-13-2

Purity & Quality Control

Batch: S493301 Water]＜1 mg/mL]false]Ethanol]＜1 mg/mL]false]5%TFA]33mg/ml mg/mL]false Purity: 98%

Lithium carbonate Related Products

Related Targets	D1 receptor D2 receptor D3 receptor D5 receptor DAT D4 receptor	Click to Expand
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Signaling Pathway

Dopamine Receptor Signaling Pathway

Biological Activity

Description	Lithium carbonate (Li2CO3) is an inorganic compound that is valuable and effective agent in the treatment and prophylaxis of mood disorders, particularly bipolar disorder (BD). Lithium carbonate is able to alter D2 dopamine receptors response.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06396312	Recruiting	Depressive; Disorder Major Single Episode Major With Psychotic Symptoms\|Depressive; Disorder Major Single Episode Major (Without Psychotic Symptoms)\|Depressive Disorder Major Recurrent With Psychotic Symptoms\|Depressive Disorder Major Recurrent Without Psychotic Symptoms\|Depressive Disorder Treatment-Resistant Class I or II\|Depressive Disorder Major Moderate\|Depressive Disorder Major Severe	Max-Planck-Institute of Psychiatry	April 2 2024	--
NCT06134349	Recruiting	Bipolar Disorder	Leiden University Medical Center	March 13 2024	--
NCT05982340	Recruiting	Acute Kidney Injury Due to Sepsis\|Proximal Tubule Function\|Lithium Clearance	University Hospital of North Norway	August 1 2023	--
NCT05044611	Recruiting	Bipolar Disorder	Assistance Publique - Hôpitaux de Paris	January 11 2023	Phase 4
NCT05648435	Completed	Acute Kidney Injury	University Hospital of North Norway	December 7 2022	--

References

Chemical Information & Solubility

Molecular Weight	73.89	Formula	CLi₂O₃
CAS No.	554-13-2	SDF	--
Smiles	[Li+].[Li+].C(=O)([O-])[O-]
Storage (From the date of receipt)	3 years-21°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-21°C powder		1 month-20°Cin solvent

In vitro
Batch:

Water : ＜1 mg/mL

Ethanol : ＜1 mg/mL

5%TFA : 33mg/ml mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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