Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3))

Synonyms: LM 609

Catalog No.A2991 Purity:99%

Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3)) is an IgG1 monoclonal antibody targeting αvβ3 integrin. It inhibits angiogenesis and melanoma tumor growth and can be used to research anticancer. MW :144.18 KD.

Purity & Quality Control

Batch: A299101 Purity: 99% Protein concentration: 16.91mg/ml Endotoxin Level: ＜1EU/mg

Choose Selective Integrin Inhibitors

Name	Citation	Integrin
Cilengitide trifluoroacetate	66	+++
A-205804	5	++
Cyclo(RGDyK)	13	++
SB273005	25	++++
RGD (Arg-Gly-Asp) Peptides	✔
ATN-161	✔
Cyclo(-RGDfK) TFA	✔

Expand to Check More

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description	Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3)) is an IgG1 monoclonal antibody targeting αvβ3 integrin. It inhibits angiogenesis and melanoma tumor growth and can be used to research anticancer. MW :144.18 KD.

References
[1] Hersey P, et al. Cancer. 2010 Mar 15;116(6):1526-34.

References

[1] Hersey P, et al. Cancer. 2010 Mar 15;116(6):1526-34.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	892553-42-3
Molecular Weight	144.18
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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