Home JAK/STAT JAK inhibitor - IFN inhibitor Creatine For research use only.

Creatine

Synonyms: Methylguanidoacetic acid

Creatine (Methylguanidoacetic acid) is a nitrogenous organic acid that occurs naturally in vertebrates. It facilitates the recycling of adenosine triphosphate (ATP) primarily in muscle and brain tissue.Creatine can inhibits the JAK-STAT1 signal transmission by inhibiting the interaction of IFN-γ receptors with JAK2 in an ATP-independent manner, thereby inhibiting downstream pro-inflammatory gene expression.

Creatine Chemical Structure

Creatine Chemical Structure

CAS No. 57-00-1

Purity & Quality Control

Batch: S558801 Water]18 mg/mL]true]DMSO]Insoluble]false]]]false Purity: 98%
98

Creatine Related Products

Signaling Pathway

JAK Signaling Pathways

JAK Signaling Pathway

Biological Activity

Description Creatine (Methylguanidoacetic acid) is a nitrogenous organic acid that occurs naturally in vertebrates. It facilitates the recycling of adenosine triphosphate (ATP) primarily in muscle and brain tissue.Creatine can inhibits the JAK-STAT1 signal transmission by inhibiting the interaction of IFN-γ receptors with JAK2 in an ATP-independent manner, thereby inhibiting downstream pro-inflammatory gene expression.
Targets
JAK2 [1]
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Chemical Information & Solubility

Molecular Weight 131.13 Formula

C4H9N3O2
CAS No. 57-00-1 SDF --
Smiles CN(CC(=O)O)C(=N)N
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 18 mg/mL (超声加热十分钟，60℃)

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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