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Technical Data
| Formula | C4H9N3O2 |
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| Molecular Weight | 131.13 | CAS No. | 57-00-1 | |
| Solubility (25°C)* | In vitro | Water | 18 mg/mL warmed with 50ºC water bath (137.26 mM) | |
| DMSO | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Creatine (Methylguanidoacetic acid) is a nitrogenous organic acid that occurs naturally in vertebrates. It facilitates the recycling of adenosine triphosphate (ATP) primarily in muscle and brain tissue.Creatine can inhibits the JAK-STAT1 signal transmission by inhibiting the interaction of IFN-γ receptors with JAK2 in an ATP-independent manner, thereby inhibiting downstream pro-inflammatory gene expression. | |
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Protocol (from reference)
Selleck's Creatine has been cited by 3 publications
| MiR-217-5p inhibits smog (PM2.5)-induced inflammation and oxidative stress response of mouse lung tissues and macrophages through targeting STAT1 [ Aging (Albany NY), 2022, 14(16):6796-6808] | PubMed: 36040387 |
| Activating a collaborative innate-adaptive immune response to control metastasis [ Cancer Cell, 2021, S1535-6108(21)00445-1] | PubMed: 34478639 |
| Identification of testicular Foxq1 as a critical modulator of lactate metabolism in mouse Sertoli cells [ Histochem Cell Biol, 2021, 156(3):227-237] | PubMed: 34091745 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.