Home Immunology & Inflammation Nrf2 activator - Sirtuin activator - Apoptosis related activator - Lipoxygenase inhibitor - COX inhibitor - IκB/IKK inhibitor - DNA/RNA Synthesis inhibitor cis-Resveratrol For research use only.

cis-Resveratrol

Synonyms: cis-RESV, cRes, (Z)-Resveratrol

cis-Resveratrol (cis-RESV, cRes, (Z)-Resveratrol) is the Cis isomer of Resveratrol. Resveratrol is a natural phenolic compound with anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol is an inhibitor of pregnane X receptor (PXR) and an activator of Nrf2 and SIRT1 and may induce apoptosis. Resveratrol also inhibits a wide spectrum of targets including 5-lipoxygenase (LOX), cyclooxygenase (COX), IKKβ, DNA polymerases α and δ with IC50 of 2.7 μM, <1 μM, 1 μM, 3.3 μM and 5 μM, respectively.

cis-Resveratrol Chemical Structure

cis-Resveratrol Chemical Structure

CAS No. 61434-67-1

Purity & Quality Control

Batch: S316801 DMSO]46 mg/mL]false]Ethanol]46 mg/mL]false]Water]Insoluble]false Purity: 98.45%
98.45

cis-Resveratrol Related Products

Biological Activity

Description cis-Resveratrol (cis-RESV, cRes, (Z)-Resveratrol) is the Cis isomer of Resveratrol. Resveratrol is a natural phenolic compound with anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol is an inhibitor of pregnane X receptor (PXR) and an activator of Nrf2 and SIRT1 and may induce apoptosis. Resveratrol also inhibits a wide spectrum of targets including 5-lipoxygenase (LOX), cyclooxygenase (COX), IKKβ, DNA polymerases α and δ with IC50 of 2.7 μM, <1 μM, 1 μM, 3.3 μM and 5 μM, respectively.
Targets
PXR [1] Nrf2 [2] SIRT1 [2] COX [3]
(Cell-free assay)		 IKKβ [3]
(Cell-free assay)		 Click to View More Targets
1 μM 1 μM
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05343741 Recruiting
Psychological Distress
Universidad de las Americas - Quito
 October 17 2022 --
NCT04886635 Recruiting
Cancer of Esophagus
Bas P. L. Wijnhoven|Erasmus Medical Center
 March 9 2021 --

Chemical Information & Solubility

Molecular Weight 228.24 Formula

C14H12O3
CAS No. 61434-67-1 SDF --
Smiles OC1=CC=C(C=C1)\C=C/C2=CC(=CC(=C2)O)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 46 mg/mL ( (201.54 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 46 mg/mL

Water : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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