Home Biosimilar Antibodies Cytoskeletal Signaling Integrin null Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7) For research use only.
Not for use in humans.

Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7)

Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7) is a fully human monoclonal immunoglobulin G2 antibody that targets the alpha4beta7 integrin and prevents interaction with MADCAM-1. It has the potential to be used in research on inflammatory bowel disease (IBD). MW: 143.8 kD.

Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7)

Purity & Quality Control

Choose Selective Integrin Inhibitors

Name Citation Integrin
Cilengitide trifluoroacetate 66
A-205804 5
Cyclo(RGDyK) 13
SB273005 25
RGD (Arg-Gly-Asp) Peptides
ATN-161
Cyclo(-RGDfK) TFA
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7) is a fully human monoclonal immunoglobulin G2 antibody that targets the alpha4beta7 integrin and prevents interaction with MADCAM-1. It has the potential to be used in research on inflammatory bowel disease (IBD). MW: 143.8 kD.

Product Details

CAS No. 1342290-43-0
Molecular Weight 143.8
Isotype Human IgG2
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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