Home Microbiology Antiviral chemical Famciclovir For research use only.

Famciclovir

Synonyms: BRL-42810

Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.

Famciclovir Chemical Structure

Famciclovir Chemical Structure

CAS No. 104227-87-4

Purity & Quality Control

Batch: S246701 DMSO]64 mg/mL]false]Water]64 mg/mL]false]Ethanol]48 mg/mL]false Purity: 99.98%
99.98

Famciclovir Related Products

Biological Activity

Description Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05283551 Unknown status
Multiple Sclerosis
Queen Mary University of London
 November 25 2020 Phase 2
NCT00878072 Completed
Herpes Labialis
Novartis Pharmaceuticals|Novartis
 March 25 2009 Phase 2|Phase 3
NCT01154543 Completed
HIV Positive|Herpes Simplex Genital
Holdsworth House Medical Practice
 March 2008 --
NCT00448227 Completed
Herpes Simplex
Novartis
 October 2007 Phase 2
NCT00098059 Completed
Herpes Simplex
Novartis Pharmaceuticals|Novartis
 February 2005 Phase 3

Chemical Information & Solubility

Molecular Weight 321.33863 Formula

C14H19N5O4
CAS No. 104227-87-4 SDF Download Famciclovir SDF
Smiles CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 64 mg/mL ( (199.16 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 64 mg/mL

Ethanol : 48 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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