Home Neuronal Signaling Dopamine Receptor antagonist Amisulpride For research use only.

Amisulpride

Synonyms: DAN-2163

Amisulpride (DAN-2163) is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.

Amisulpride Chemical Structure

Amisulpride Chemical Structure

CAS No. 71675-85-9

Purity & Quality Control

Amisulpride Related Products

Signaling Pathway

Dopamine Receptor Signaling Pathways

Dopamine Receptor Signaling Pathway

Biological Activity

Description Amisulpride (DAN-2163) is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.
Targets
Dopamine receptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04849650 Completed
Renal Disease End Stage
Acacia Pharma Ltd
 June 3 2021 Phase 1
NCT00245674 Completed
Schizophrenia
Sanofi
 June 2005 Phase 4

Chemical Information & Solubility

Molecular Weight 369.48 Formula

C17H27N3O4S
CAS No. 71675-85-9 SDF Download Amisulpride SDF
Smiles CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 74 mg/mL ( (200.28 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 74 mg/mL

Water : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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