Home Immunology & Inflammation Nrf2 activator 5,7-Dihydroxychromone For research use only.

5,7-Dihydroxychromone

Synonyms: DHC

5,7-Dihydroxychromone (DHC), a natural antioxidant extracted from plants, is a potent activator of Nrf2/ARE signal. 5,7-dihydroxychromone also is a potent activator of PPARγ and LXRα. 5,7-Dihydroxychromone may contributes to regulate blood glucose levels and shows anti-diabetic property.

5,7-Dihydroxychromone Chemical Structure

5,7-Dihydroxychromone Chemical Structure

CAS No. 31721-94-5

Purity & Quality Control

Batch: E002301 DMSO]36 mg/mL]false]Ethanol]9 mg/mL]false]Water]Insoluble]false Purity: 99.98%
99.98

5,7-Dihydroxychromone Related Products

Biological Activity

Description

5,7-Dihydroxychromone (DHC), a natural antioxidant extracted from plants, is a potent activator of Nrf2/ARE signal. 5,7-dihydroxychromone also is a potent activator of PPARγ and LXRα. 5,7-Dihydroxychromone may contributes to regulate blood glucose levels and shows anti-diabetic property.
Targets
LXRα [1] Nrf2/ARE [1] PPARγ [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05399550 Withdrawn
Acute Ischemic Stroke
Hoffmann-La Roche
 June 22 2022 Phase 2

Chemical Information & Solubility

Molecular Weight 178.14 Formula

C9H6O4
CAS No. 31721-94-5 SDF --
Smiles OC1=CC(=C2C(=O)C=COC2=C1)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 36 mg/mL ( (202.08 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 9 mg/mL

Water : Insoluble


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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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