Home Metabolism Casein Kinase inhibitor - CDK inhibitor 5,6-Dichlorobenzimidazole 1-beta-D-ribofuranoside For research use only.

5,6-Dichlorobenzimidazole 1-beta-D-ribofuranoside

Synonyms: DRB

5,6-Dichlorobenzimidazole riboside(DRB) is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II and CDKs. It trigger p53-dependent apoptosis of human colon adenocarcinoma cells without inducing genotoxic stress to healthy cells.

5,6-Dichlorobenzimidazole 1-beta-D-ribofuranoside Chemical Structure

5,6-Dichlorobenzimidazole 1-beta-D-ribofuranoside Chemical Structure

CAS No. 53-85-0

Purity & Quality Control

Batch: E291401 DMSO]64 mg/mL]false]Ethanol]5 mg/mL]false]Water]Insoluble]false Purity: 99.73%
99.73

5,6-Dichlorobenzimidazole 1-beta-D-ribofuranoside Related Products

Biological Activity

Description 5,6-Dichlorobenzimidazole riboside(DRB) is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II and CDKs. It trigger p53-dependent apoptosis of human colon adenocarcinoma cells without inducing genotoxic stress to healthy cells.
Targets
Casein Kinase 2 [1]
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Chemical Information & Solubility

Molecular Weight 319.14 Formula

C12H12Cl2N2O4
CAS No. 53-85-0 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 64 mg/mL ( (200.53 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 5 mg/mL

Water : Insoluble


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In vivo
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