Home Immunology & Inflammation TLR agonist 1V209 (TLR7 agonist T7) For research use only.

1V209 (TLR7 agonist T7)

Synonyms: T7

1V209 (T7, TLR7 agonist T7) is an agonist of Toll-like receptor 7 (TLR7) with anti-tumor effects. 1V209 can be used as vaccine adjuvants, enhances antigen specific humoral and cellular immune responses.

1V209 (TLR7 agonist T7) Chemical Structure

1V209 (TLR7 agonist T7) Chemical Structure

CAS No. 1062444-54-5

Purity & Quality Control

Batch: S007801 DMSO]72 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 99.86%
99.86

1V209 (TLR7 agonist T7) Related Products

Biological Activity

Description 1V209 (T7, TLR7 agonist T7) is an agonist of Toll-like receptor 7 (TLR7) with anti-tumor effects. 1V209 can be used as vaccine adjuvants, enhances antigen specific humoral and cellular immune responses.
Targets
TLR7 [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06007794 Not yet recruiting
Cancer|Post-cancer|Hematology
Hospices Civils de Lyon
 April 1 2024 Not Applicable
NCT06112483 Not yet recruiting
Specific Learning Disorder|Intellectual Disability Mild to Moderate|Autism Spectrum Disorder|Attention Deficit Hyperactivity Disorder|Physical Disability
Chinese University of Hong Kong
 November 15 2023 --
NCT06203665 Completed
Atelectasis|Compliance Patient
Panagiota Griva|National and Kapodistrian University of Athens
 June 7 2023 Not Applicable
NCT05594550 Not yet recruiting
Acute Respiratory Distress Syndrom (SARS-Cov 2)
Centre Hospitalier Universitaire Dijon
 October 2022 --

Chemical Information & Solubility

Molecular Weight 359.34 Formula
C16H17N5O5
CAS No. 1062444-54-5 SDF --
Smiles COCCOC1=NC(=C2C(=N1)N(C(=O)N2)CC3=CC=C(C=C3)C(=O)O)N
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 72 mg/mL ( (200.36 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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