Home DNA Damage/DNA Repair -Epigenetics Sirtuin SIRT6 Selective Inhibitors | Activators
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SIRT6 Selective Inhibitors | Activators

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8909 UBCS039 UBCS039 is the first synthetic SIRT6 activator with EC50 of 38 μM,induces a time-dependent activation of autophagy in several human tumor cell lines. Selective SIRT6, EC50: 38 μM
S8627 OSS_128167 OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor with IC50 values of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-viral effect in HBV transcription and replication. Pan SIRT6, IC50: 89 μM