Home Neuronal Signaling 5-HT Receptor agonist Urapidil HCl For research use only.

Urapidil HCl

Urapidil HCl is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.

Urapidil HCl Chemical Structure

Urapidil HCl Chemical Structure

CAS No. 64887-14-5

Purity & Quality Control

Batch: S202501 Water]85 mg/mL]false]DMSO]24 mg/mL]false]Ethanol]1 mg/mL]false Purity: 99.08%
99.08

Urapidil HCl Related Products

Signaling Pathway

5-HT Receptor Signaling Pathways

5-HT Receptor Signaling Pathway

Biological Activity

Description Urapidil HCl is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.
Targets
5-HT1A [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03076099 Unknown status
Anesthesia
Nan Jiang|First Affiliated Hospital Sun Yat-Sen University
 January 1 2016 Not Applicable
NCT05537194 Completed
Hypoxia
University Hospital Caen
 January 1 1963 --

Chemical Information & Solubility

Molecular Weight 423.94 Formula

C20H29N5O3.HCl
CAS No. 64887-14-5 SDF Download Urapidil HCl SDF
Smiles CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC.Cl
Storage (From the date of receipt)

In vitro
Batch:

Water : 85 mg/mL

DMSO : 24 mg/mL ( (56.61 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 1 mg/mL


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In vivo
Batch:

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In vivo Formulation Calculator

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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