Serotonin (5-HT) HCl

Serotonin (5-HT) HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.

Serotonin (5-HT) HCl Chemical Structure

Serotonin (5-HT) HCl Chemical Structure

CAS No. 153-98-0

Purity & Quality Control

Serotonin (5-HT) HCl Related Products

Biological Activity

Description Serotonin (5-HT) HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.
Targets
5-HT [1]
In vitro
In vitro Serotonin stimulates acid–base transport by the anterior stomach region of the midgut in vitro. The function of this stimulation is assumed to be maintenance of optimal conditions for digestion and absorption of nutrients rather than regulation of hemolymph acid–base homeostasis. [1]
Experimental Result Images Methods Biomarkers Images PMID
Western blot FAS / L-FABP1 / pS79-ACC / ACC / SREBP1 / SCD1 / pPPARα / PPAR-γ LC3β / ATG3 / pS65-4EBP1 / Beclin-1 / SIRT1 / p62 / FOXO3a 30409162
Growth inhibition assay Cell proliferation 30409162
In Vivo
In vivo The role of serotonin in the regulation of larval Aedes aegypti hemolymph composition is investigated in vivo using two reuptake inhibitors (SSRIs), alaproclate HCl and 6-nitroquipazine maleate, and the receptor antagonist methiothepin mesylate. [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06381479 Recruiting
Stress|Sleep Disorder
National Taiwan Sport University|Bened Biomedical Co. Ltd.
April 19 2024 Not Applicable
NCT06361368 Not yet recruiting
Insomnia
National Yang Ming University|Bened Biomedical Co. Ltd.
April 2024 Not Applicable

Chemical Information & Solubility

Molecular Weight 212.68 Formula

C10H12N2O.HCl

CAS No. 153-98-0 SDF Download Serotonin (5-HT) HCl SDF
Smiles C1=CC2=C(C=C1O)C(=CN2)CCN.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 43 mg/mL ( (202.18 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 43 mg/mL

Ethanol : 43 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

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