Home Neuronal Signaling 5-HT Receptor inhibitor Trazodone HCl For research use only.

Trazodone HCl

Synonyms: AF-1161, KB-831

Trazodone HCl (AF-1161, KB-831) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.

Trazodone HCl Chemical Structure

Trazodone HCl Chemical Structure

CAS No. 25332-39-2

Purity & Quality Control

Batch: S258201 DMSO]4 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 100%
100

Trazodone HCl Related Products

Signaling Pathway

5-HT Receptor Signaling Pathways

5-HT Receptor Signaling Pathway

Biological Activity

Description Trazodone HCl (AF-1161, KB-831) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.
Targets
5-HT [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06286189 Recruiting
Obstructive Sleep Apnea
Brigham and Women''s Hospital
 January 1 2024 Phase 1|Phase 2
NCT02086929 Completed
Major Depressive Disorder
Aziende Chimiche Riunite Angelini Francesco S.p.A
 December 2012 Phase 3
NCT01097980 Completed
Sexual Dysfunction
Beitou Armed Forces Hospital Taipei Taiwan
 April 2010 Not Applicable

Chemical Information & Solubility

Molecular Weight 408.32 Formula

C19H22ClN5O.HCl
CAS No. 25332-39-2 SDF Download Trazodone HCl SDF
Smiles C1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 4 mg/mL ( (9.79 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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