Telisotuzumab vedotin

Synonyms: Teliso-V, ABBV-399

Catalog No.D4046 Purity:99.1%

Telisotuzumab vedotin (Teliso-V, ABBV-399) is an antibody-drug conjugate (ADC) composed of the anti–c-Met humanized monoclonal antibody coupled to the cytotoxic monomethyl auristatin E (MMAE) through a mc-val-cit-PABC type linker. Telisotuzumab vedotin can be used for research on advanced solid tumours.

CAS No. 1714088-51-3

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Purity & Quality Control

Batch: D404601 Purity: 99.1% Protein concentration: 3.28mg/ml Endotoxin Level: ＜1EU/mg

99.1

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Glesatinib	✔	SMO
Terevalefim	✔
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Pulsatilla saponin D	✔
Sodium L-ascorbyl-2-phosphate	✔
Norcantharidin	✔	EGFR

Expand to Check More

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description	Telisotuzumab vedotin (Teliso-V, ABBV-399) is an antibody-drug conjugate (ADC) composed of the anti–c-Met humanized monoclonal antibody coupled to the cytotoxic monomethyl auristatin E (MMAE) through a mc-val-cit-PABC type linker. Telisotuzumab vedotin can be used for research on advanced solid tumours.

References
[1] Strickler JH, et al. J Clin Oncol. 2018 Nov 20;36(33):3298-3306.

References

[1] Strickler JH, et al. J Clin Oncol. 2018 Nov 20;36(33):3298-3306.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1714088-51-3
DAR	3.71
ADC antiody	Telisotuzumab
ADC cytotoxin	MMAE
Formulation	1xPBS
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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