Home Biosimilar Antibodies Protein Tyrosine Kinase PDGFR null Rinucumab (Anti-PDGFRB / CD140b) For research use only.
Not for use in humans.

Rinucumab (Anti-PDGFRB / CD140b)

Synonyms: REGN 2176

Rinucumab (Anti-PDGFRB / CD140b) is an anti-platelet-derived growth factor receptor beta (anti-PDGFR-beta) monoclonal antibody and has a potential to study neovascular age-related macular degeneration. MW: 145.5 kD.

Rinucumab (Anti-PDGFRB / CD140b)

Purity & Quality Control

Batch: A237801 Purity: 99% Protein concentration: 5.74mg/ml Endotoxin Level: ＜1EU/mg
99

Choose Selective PDGFR Inhibitors

Name Citation PDGFR PDGFRα PDGFRβ Others
Dovitinib (TKI-258) 49 FLT3,c-Kit,VEGFR3/FLT4
Linifanib (ABT-869) 32 VEGFR1/FLT1,CSF-1R,VEGFR2/KDR
Crenolanib 92
Masitinib 40 Kit,Lyn B,Abl1
Amuvatinib (MP-470) 19 c-Kit (D816H),FLT3 (D835Y)
Motesanib Diphosphate (AMG-706) 12 VEGFR1,VEGFR2,VEGFR2/Flk1
Orantinib (SU6668) 20
CP-673451 32
Ki8751 20 VEGFR2,c-Kit
Telatinib 5 c-Kit,VEGFR3,VEGFR2
PP121 5 Hck,VEGFR,mTOR
MK-2461 4 c-Met (M1250T),c-Met (Y1235D),c-Met (Y1230H)
Tyrphostin AG 1296 14 c-Kit (Swiss 3T3),FGFR (Swiss 3T3)
Tyrphostin 9 1 EGFR
Dovitinib (TKI258) Lactate monohydrate 30 FLT3,c-Kit,FGFR1
AZD2932 3 Flt3,VEGFR-2,c-Kit
Sennoside B
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Rinucumab (Anti-PDGFRB / CD140b) is an anti-platelet-derived growth factor receptor beta (anti-PDGFR-beta) monoclonal antibody and has a potential to study neovascular age-related macular degeneration. MW: 145.5 kD.

Product Details

CAS No. 1569263-06-4
Molecular Weight 145.5 kDa
Isotype Human IgG4SP
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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