Rilotumumab (Anti-HGF / SF)

Synonyms: AMG 102

Rilotumumab (Anti-HGF / SF) is a monoclonal antibody that inhibits HGF/MET-driven signaling. Rilotumumab shows anti-tumor activity, and can be used in castration-resistant prostate cancer (CRPC) and solid tumor research. MW: 145.5 KD.

Rilotumumab (Anti-HGF / SF)

Purity & Quality Control

Batch: A246901 Purity: 99% Protein concentration: 14.86mg/ml Endotoxin Level: <1EU/mg
99

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Name Citation c-Met Others
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BMS-777607 56 Axl,RON,Tyro3
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PF-04217903 22
MGCD-265 analog 12 RON,VEGFR2,VEGFR1
BMS-754807 50 Insulin Receptor,IGF-1R,TrkB
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AMG-208 0
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AMG-458 0
Tepotinib 18
NVP-BVU972 1
Savolitinib (AZD6094) 15 p-Met
S49076 1 Mer,Axl,FGFR3
Merestinib (LY2801653) 9
AMG 337 2
NPS-1034 3 Axl
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Rilotumumab (Anti-HGF / SF) is a monoclonal antibody that inhibits HGF/MET-driven signaling. Rilotumumab shows anti-tumor activity, and can be used in castration-resistant prostate cancer (CRPC) and solid tumor research. MW: 145.5 KD.

Product Details

CAS No. 872514-65-3
Molecular Weight 145.5 kDa
Isotype Human IgG2SA
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac,pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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