Mgd010 (Anti-CD79b & CD32b) CD markers inhibitor | Read Reviews & Product Use Citations

Mgd010 is a bispecific dual-affinity retargeting (DART®) molecule that targets both the B cell surface proteins CD32B and CD79B, delivering a co-inhibitory signal to dampen B cell activation. It holds potential for treating autoimmune diseases such as rheumatoid arthritis and other inflammatory conditions. MW: 108.77 KD.

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SDS
Datasheet

Specificity

Name	Citation	CD38	CD45	CD39	CD88	CD73	Others
RBN013209	0	++
MK-0159	0	+++
CD38 inhibitor 1 (compound 78c)	7	+++
AB680	0					++++
NQ301	1		+				TXA2 receptor
SodiuM Metatungstate	3			++
PMX-53	3				✔
LY-3475070	2					✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Mgd010 is a bispecific dual-affinity retargeting (DART®) molecule that targets both the B cell surface proteins CD32B and CD79B, delivering a co-inhibitory signal to dampen B cell activation. It holds potential for treating autoimmune diseases such as rheumatoid arthritis and other inflammatory conditions. MW: 108.77 KD.

Product Details

CAS No.	N/A
Source	CHO
Storage (From the date of receipt)	-80℃(avoid freeze-thaw cycles)

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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