Home GPCR & G Protein Prostaglandin Receptor antagonist MF-766 For research use only.

MF-766

Synonyms: Compound 9a

MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM.

MF-766 Chemical Structure

MF-766 Chemical Structure

CAS No. 1050656-06-8

Purity & Quality Control

Batch: E061201 DMSO]96 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 99.8%
99.8

MF-766 Related Products

Biological Activity

Description MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM.
Targets
EP4 [1]
0.23 nM(Ki)

Chemical Information & Solubility

Molecular Weight 478.46 Formula

C27H21F3N2O3
CAS No. 1050656-06-8 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 96 mg/mL ( (200.64 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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