Catalog No.	Product Name	Information	Selective / Pan	IC50 / Ki
S3346	1-Methylnicotinamide chloride	1-Methylnicotinamide (1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium, Trigonellamide) chloride is an active endogenous metabolite of nicotinamide that exhibits anti-inflammatory and anti-thrombotic activities. 1-Methylnicotinamide enhances tumor vasculature formation and markedly increases prostacyclin (PGI2) generation.	Selective
S0305	RO1138452	RO1138452 (CAY10441) is a potent and selective antagonist of IP (prostacyclin, PGI2) receptor with pKi of 9.3 and 8.7 in human platelets and a recombinant IP receptor system, respectively.	Selective	PGI2, pKi: 9.3; PGI2, pKi: 8.7
S0325	Treprostinil sodium	Treprostinil sodium (UT-15, Remodulin, Orenitram, Tyvaso, Trevyent) is a potent agonist of DP1, EP2 and IP receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.	Pan	IP, Ki: 32 nM

PGI2 Selective Agonists | Antagonists | Modulators