Home Biosimilar Antibodies Immunology & Inflammation CD markers inhibitor Hpn328 (Anti-CD3e & DLL3 & Serum Albumin) For research use only.
Not for use in humans.

Hpn328 (Anti-CD3e & DLL3 & Serum Albumin)

Synonyms: Gocatamig, MK-6070

HPN328 is a humanized, trispecific T-cell activating construct (TriTAC) targeting CD3 for T-cell engagement, HSA for half-life extension, and DLL3 on tumor cells. It induces potent T-cell-mediated cytotoxicity against DLL3-expressing small cell lung cancer (SCLC), leading to tumor regression and long-term anti-tumor immunity. M.W 53.06 kDa.

Hpn328 (Anti-CD3e & DLL3 & Serum Albumin)

Purity & Quality Control

Choose Selective CD markers Inhibitors

Name Citation CD38 CD45 CD39 CD88 CD73 Others
RBN013209 0
MK-0159 0
CD38 inhibitor 1 (compound 78c) 5
AB680 0
NQ301 1 TXA2 receptor
SodiuM Metatungstate 3
PMX-53
LY-3475070
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description HPN328 is a humanized, trispecific T-cell activating construct (TriTAC) targeting CD3 for T-cell engagement, HSA for half-life extension, and DLL3 on tumor cells. It induces potent T-cell-mediated cytotoxicity against DLL3-expressing small cell lung cancer (SCLC), leading to tumor regression and long-term anti-tumor immunity. M.W 53.06 kDa.

Product Details

CAS No. N/A
Source CHO
Storage
(From the date of receipt)		 -80℃

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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