Home Proteases Tyrosinase inhibitor Hexylresorcinol For research use only.

Hexylresorcinol

Synonyms: 4-Hexylresorcinol

Hexylresorcinol (4-Hexylresorcinol) is an organic compound with local anaesthetic, antiseptic and anthelmintic properties, is a potent inhibitor of mushroom tyrosinase. The IC50 values of hexylresorcinol for monophenolase is 1.24 μM and for diphenolase is 0.85 μM.

Hexylresorcinol Chemical Structure

Hexylresorcinol Chemical Structure

CAS No. 136-77-6

Purity & Quality Control

Hexylresorcinol Related Products

Biological Activity

Description Hexylresorcinol (4-Hexylresorcinol) is an organic compound with local anaesthetic, antiseptic and anthelmintic properties, is a potent inhibitor of mushroom tyrosinase. The IC50 values of hexylresorcinol for monophenolase is 1.24 μM and for diphenolase is 0.85 μM.
Targets
diphenolase [1]
(Cell-free assay)		 monophenolase [1]
(Cell-free assay)
0.85 μM 1.24 μM
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04345094 Completed
Photoaging
Sytheon Ltd.
 July 1 2019 Not Applicable

Chemical Information & Solubility

Molecular Weight 194.27 Formula

C12H18O2
CAS No. 136-77-6 SDF Download Hexylresorcinol SDF
Smiles CCCCCCC1=C(C=C(C=C1)O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 38 mg/mL ( (195.6 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 38 mg/mL

Water : Insoluble


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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