Emibetuzumab (Anti-HGFR / c-Met)

Synonyms: LY2875358

Emibetuzumab (Anti-HGFR / c-Met) is a humanized bivalent MET antibody targeting both HGF-dependent and HGF-independent MET pathway activation and tumor growth. It can be used in study of cancer. MW :144.56 KD.

Emibetuzumab (Anti-HGFR / c-Met)

Purity & Quality Control

Batch: A266201 Purity: 99% Protein concentration: 8.51mg/ml Endotoxin Level: <1EU/mg
99

Choose Selective c-Met Inhibitors

Name Citation c-Met Others
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BMS-777607 56 Axl,RON,Tyro3
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PF-04217903 22
MGCD-265 analog 12 RON,VEGFR2,VEGFR1
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AMG-208 0
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AMG-458 0
Tepotinib 18
NVP-BVU972 1
Savolitinib (AZD6094) 16 p-Met
S49076 1 Mer,Axl,FGFR3
Merestinib (LY2801653) 9
AMG 337 2
NPS-1034 3 Axl
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Emibetuzumab (Anti-HGFR / c-Met) is a humanized bivalent MET antibody targeting both HGF-dependent and HGF-independent MET pathway activation and tumor growth. It can be used in study of cancer. MW :144.56 KD.

Product Details

CAS No. 1365287-97-3
Molecular Weight 144.56
Isotype Human IgG4SP
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac,pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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