Cabiralizumab (Anti-CSF1R / M-CSFR / CD115)

Synonyms: FPA 008

Catalog No.A2644 Purity:99%

Cabiralizumab (Anti-CSF1R / M-CSFR / CD115) is an monoclonal antibody (MAb) targeting CSF1R. It can be used in the research of rheumatoid arthritis (RA), melanoma, kidney cancer, or non-small cell lung cancer. MW :146.3 KD.

Purity & Quality Control

Batch: A264401 Purity: 99% Protein concentration: 5.74mg/ml Endotoxin Level: ＜1EU/mg

Choose Selective CSF-1R Inhibitors

Name	Citation	CSF-1R	Others
Linifanib (ABT-869)	32	+++	VEGFR1/FLT1,FLT3,VEGFR2/KDR
OSI-930	7	++	FLT1,KDR,LCK
GW2580	15	+
Agerafenib (CEP-32496)	6	+++	LCK,c-Kit,RET
Sotuletinib (BLZ945)	29	++++

Expand to Check More

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description	Cabiralizumab (Anti-CSF1R / M-CSFR / CD115) is an monoclonal antibody (MAb) targeting CSF1R. It can be used in the research of rheumatoid arthritis (RA), melanoma, kidney cancer, or non-small cell lung cancer. MW :146.3 KD.

References
[1] Weiss SA, et al. Clin Cancer Res. 2021 Sep 1;27(17):4757-4767.

References

[1] Weiss SA, et al. Clin Cancer Res. 2021 Sep 1;27(17):4757-4767.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1613144-80-1
Molecular Weight	146.3
Isotype	Human IgG4SP
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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