Anti-FGFR1 / CD331

Catalog No.A2909 Purity:99%

Anti-FGFR1 / CD331 is a monoclonal antibody againts human fibroblast growth factor receptor 1. MW: 150 KD.

Purity & Quality Control

Batch: A290901 Purity: 99% Protein concentration: 6.57mg/ml Endotoxin Level: ＜1EU/mg

Choose Selective FGFR Inhibitors

Name	Citation	FGFR	FGFR1	FGFR2	FGFR3	FGFR4	Others
PD173074	120		++				VEGFR2
Dovitinib (TKI-258)	49		+++		+++		FLT3,c-Kit,VEGFR3/FLT4
Fexagratinib (AZD4547)	135		++++	++++	++++		KDR
Danusertib (PHA-739358)	46		++				Aurora A,Abl,TrkA
Brivanib (BMS-540215)	9		+				VEGFR2,Flk1,VEGFR1
ENMD-2076	8		+	+			FLT3,RET,Aurora A
MK-2461	4		+	++	++		c-Met (M1250T),c-Met (Y1235D),c-Met (Y1230H)
Brivanib Alaninate (BMS-582664)	2		+				VEGFR2,Flk1,VEGFR1
Tyrphostin AG 1296	14	+					PDGFR,c-Kit (Swiss 3T3)
SSR128129E	9		+
R1530	0		++				VEGFR2
FIIN-3	0		+++	++	++	++
Lucitanib (E3810) hydrochloride	1		++	+			VEGFR1,VEGFR3,VEGFR2
Sulfatinib	1		+++				VEGFR3,VEGFR1,CSF1R
ODM-203	0		+++	+++	+++	++	VEGFR3,VEGFR2,VEGFR1
Futibatinib (TAS-120)	14		++++	++++	++++	+++
ASP5878	3		++++	++++	++++	+++
Derazantinib	4		+++	++++	+++	++	RET,DDR2,PDGFRβ
H3B-6527	11					++++
Roblitinib (FGF401)	4					++++
PRN1371	2		++++	++++	+++	++	CSF1R
PD-166866	12		+
Fisogatinib (BLU-554)	8					+++
S49076	1		++	++	+++		Met,Mer,Axl
NSC12	2			+			FGF3,FGF8b,FGF22
ON123300	3		++				CDK4/CyclinD1,RET,CDK6/CyclinD1
SU5402	17		++				VEGFR2,PDGFRβ
BLU9931	18				+	+++
FIIN-2	4		+++	+++	++	++
Dovitinib (TKI258) Lactate monohydrate	30		+++		+++		FLT3,c-Kit,VEGFR3/FLT4
Zoligratinib (Debio-1347)	11		+++	+++	++	+
LY2874455	14		+++	+++	+++	+++	VEGFR2
Ferulic Acid	6		+	+
Lirafugratinib			✔
Masitinib mesylate				✔		FAK,human recombinant c-Kit,LynB
BO-264				✔		TACC3
SKLB 610			✔			PDGFR,VEGFR2
Alofanib (RPT835)			✔
Gambogenic acid	✔					EZH2

Expand to Check More

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description	Anti-FGFR1 / CD331 is a monoclonal antibody againts human fibroblast growth factor receptor 1. MW: 150 KD.

References
[1] Douglas M, et al. WO2012015674A1.

References

[1] Douglas M, et al. WO2012015674A1.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Molecular Weight	150
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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