Anti-ACVR1 / ALK-2 (DS-6016a)

Synonyms: Prafnosbart

Anti-ACVR1 / ALK-2 (DS-6016a) monoclonal antibody targeting ALK-2. It can be used in the treatment of fibrodysplasia ossificans progressiva (FOP). MW :145.56.

Anti-ACVR1 / ALK-2 (DS-6016a)

Purity & Quality Control

Choose Selective ALK Inhibitors

Name Citation ALK Others
TAE684 (NVP-TAE684) 82
AP26113-analog (ALK-IN-1) 4 EGFR(C797S/del19),IGF1R,EGFR(del19)
GSK1838705A 18 Insulin Receptor,IGF-1R
AZD3463 7 IGF-1R
ASP3026 3
ZX-29 0
MS4078 0
Ensartinib dihydrochloride 6 GOPC-ROS1,TRKC,TPM3-TRKA
Belizatinib (TSR-011) 0 TrkB,TrkA,TrkC
Repotrectinib (TPX-0005) 11 Trk receptor,ROS1,Src
Itacnosertib (TP-0184)
Zilurgisertib fumarate
ALK inhibitor 1 FAK,TSSK2
X-376
HG-14-10-04
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Anti-ACVR1 / ALK-2 (DS-6016a) monoclonal antibody targeting ALK-2. It can be used in the treatment of fibrodysplasia ossificans progressiva (FOP). MW :145.56.

Product Details

CAS No. 2566473-71-8
Molecular Weight 145.56
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac,pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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