For research use only. Not for use in humans.

Anti-AA2AR / Adenosine A2aR (3F6-9G5)

Synonyms: RDC8 Cat.No.A3147 Purity:99%

Anti-AA2AR / Adenosine A2aR (3F6-9G5) is a monoclonal antibody targeting A2A adenosine receptor. It may be an attractive target for research studies or treatments of insomnia, pain, depression, and Parkinson's disease. MW :146.66 KD.

Anti-AA2AR / Adenosine A2aR (3F6-9G5)

Quality Control

Batch: A314701 Purity: 99% Protein concentration: 5.68mg/ml Endotoxin Level: ＜1EU/mg

99

Specificity

Name	Citation	Adenosine Receptor	Adenosine receptor	Adenosine A1 receptor	Others
Taminadenant	0		+
DPCPX	1		++++
SCH-442416	0	++++
Preladenant	0	+++
Etrumadenant (AB928)	2	+++
Derenofylline (SLV320)	0	++++		++++
BAY-545	0	+
Ciforadenant (CPI-444)	2	++
Imaradenant (AZD4635)	1	+++
A2AR antagonist 1	2	++
SCH58261	7	++
Reversine	16	+			Aurora C,Aurora A,Aurora B
MIPS521	0	✔
Proxyphylline	0	✔
ZM241385	9	✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Anti-AA2AR / Adenosine A2aR (3F6-9G5) is a monoclonal antibody targeting A2A adenosine receptor. It may be an attractive target for research studies or treatments of insomnia, pain, depression, and Parkinson's disease. MW :146.66 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/10051547/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Isotype	Human IgG1
Source	CHO
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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