- Bioactive Compounds
- By Signaling Pathways
- PI3K/Akt/mTOR
- Epigenetics
- Methylation
- Immunology & Inflammation
- Protein Tyrosine Kinase
- Angiogenesis
- Apoptosis
- Autophagy
- ER stress & UPR
- JAK/STAT
- MAPK
- Cytoskeletal Signaling
- Cell Cycle
- TGF-beta/Smad
- DNA Damage/DNA Repair
- Compound Libraries
- Antibodies
- Bioreagents
- qPCR
- 2x SYBR Green qPCR Master Mix
- 2x SYBR Green qPCR Master Mix(Low ROX)
- 2x SYBR Green qPCR Master Mix(High ROX)
- Protein Assay
- Protein A/G Magnetic Beads for IP
- Anti-Flag magnetic beads
- Anti-Flag Affinity Gel
- Anti-Myc magnetic beads
- Anti-HA magnetic beads
- Magnetic Separator
- Poly DYKDDDDK Tag Peptide lyophilized powder
- Protease Inhibitor Cocktail
- Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO)
- Phosphatase Inhibitor Cocktail (2 Tubes, 100X)
- Cell Biology
- Cell Counting Kit-8 (CCK-8)
- Animal Experiment
- Mouse Direct PCR Kit (For Genotyping)
- New Products
- Contact Us
-
Australia
-
Austria
-
Belgium
-
Canada
-
China
-
Czech Republic
-
Denmark
-
Finland
-
France
-
Germany
-
Greece
-
Hong Kong
-
Hungary
-
Iceland
-
India
-
Ireland
-
Israel
-
Italy
-
Japan
-
Korea
-
Luxembourg
-
Malaysia
-
Netherlands
-
New Zealand
-
Norway
-
Poland
-
Qatar
-
Romania
-
Saudi Arabia
-
Singapore
-
Spain
-
Sweden
-
Switzerland
-
Taiwan
-
Turkey
-
United Kingdom
-
United States
-
Other Countries
Amantadine
Synonyms: 1-Adamantanamine, 1-Adamantylamine, 1-Aminoadamantane
Amantadine (1-Adamantanamine) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.Amantadine can relieve muscle stiffness, tremors, and movement disorders caused by Parkinson's disease.
Amantadine Chemical Structure
CAS No. 768-94-5
Purity & Quality Control
Batch:
S549901
4-Methylpyridine]10 mg/mL]true]DMSO]1 mg/mL]false]]]false
Purity:
98%
98
Amantadine Related Products
| Related Products | Nucleozin Arbidol HCl | Click to Expand |
|---|---|---|
| Related Compound Libraries | Anti-infection Compound Library Antibiotics compound Library Antiviral Compound Library Anti-parasitic Compound Library Gut Microbial Metabolite Library | Click to Expand |
Biological Activity
| Description | Amantadine (1-Adamantanamine) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.Amantadine can relieve muscle stiffness, tremors, and movement disorders caused by Parkinson's disease. | |
|---|---|---|
| Targets |
|
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT04530006 | Recruiting | Glioblastoma Multiforme |
CancerCare Manitoba|University of Manitoba|The Metabolomics Innovation Centre|BioMark Diagnostics Inc.|Canadian Institutes of Health Research (CIHR) |
December 2 2020 | Not Applicable |
| NCT02277938 | Unknown status | Cancer |
University of Manitoba|BioMark Technologies Inc.|St. Boniface Hospital |
August 2013 | -- |
| NCT01491529 | Completed | Dyskinesias|Parkinson Disease|Movement Disorders|Parkinsonian Disorders|Anti-Dyskinesia Agents |
Novartis Pharmaceuticals|Novartis |
April 2012 | Phase 2 |
| NCT01467258 | Completed | Healthy Metabolism |
University of Manitoba|St. Boniface Hospital |
November 2011 | Not Applicable |
Chemical Information & Solubility
| Molecular Weight | 151.25 | Formula | C10H17N |
| CAS No. | 768-94-5 | SDF | -- |
| Smiles | C1C2CC3CC1CC(C2)(C3)N | ||
| Storage (From the date of receipt) | |||
|
In vitro |
4-Methylpyridine : 10 mg/mL DMSO : 1 mg/mL ( (6.61 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.) |
Molecular Weight Calculator |
|
In vivo Add solvents to the product individually and in order. |
In vivo Formulation Calculator |
||||
Preparing Stock Solutions
Molarity Calculator
In vivo Formulation Calculator (Clear solution)
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
mg/kg
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
% DMSO
%
% Tween 80
% ddH2O
%DMSO
%
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.
* Indicates a Required Field
Tags: buy Amantadine | Amantadine supplier | purchase Amantadine | Amantadine cost | Amantadine manufacturer | order Amantadine | Amantadine distributor
Products are for research use only. Not for human use. We do not sell to patients.
©Copyright 2013 Selleck Chemicals. All Rights Reserved.