Home Proteases Tyrosinase inhibitor 4-Chlorosalicylic acid For research use only.

4-Chlorosalicylic acid

Synonyms: 4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid

4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) was used in sensitive spectrofluorometric determination of terbium in mixed rare earths and preparation of poly(4-chlorosalicylic acid-formaldehyde) via condensation with formaldehyde. 4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.

4-Chlorosalicylic acid Chemical Structure

4-Chlorosalicylic acid Chemical Structure

CAS No. 5106-98-9

Purity & Quality Control

Batch: S369101 DMSO]34 mg/mL]false]Ethanol]34 mg/mL]false]Water]Insoluble]false Purity: 99.81%
99.81

4-Chlorosalicylic acid Related Products

Biological Activity

Description 4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) was used in sensitive spectrofluorometric determination of terbium in mixed rare earths and preparation of poly(4-chlorosalicylic acid-formaldehyde) via condensation with formaldehyde. 4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.

Chemical Information & Solubility

Molecular Weight 172.57 Formula

C7H5ClO3
CAS No. 5106-98-9 SDF Download 4-Chlorosalicylic acid SDF
Smiles C1=CC(=C(C=C1Cl)O)C(=O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 34 mg/mL ( (197.02 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 34 mg/mL

Water : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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