Choose Your Country or Region

2',3'-Dideoxyadenosine

Name: 2',3'-Dideoxyadenosine
Brand: Selleck Chemicals
SKU: S5979
Rating: 5 (1 reviews)

Synonyms: ddA, ddAdo

Catalog No.S5979 Purity:99.98%

2',3'-Dideoxyadenosine (ddA, ddAdo) is an anti-human immunodeficiency virus agent against human immunodeficiency virus (HIV) and human hepatitis B virus (HBV) replication.

2',3'-Dideoxyadenosine Chemical Structure

CAS No. 4097-22-7

Purity & Quality Control

Batch: S597901 DMSO]47 mg/mL]false]Water]47 mg/mL]false]Ethanol]Insoluble]false Purity: 99.98%

99.98

2',3'-Dideoxyadenosine Related Products

Related Products	Ebselen	Click to Expand
Related Compound Libraries	Anti-infection Compound Library Antibiotics compound Library Antiviral Compound Library Anti-parasitic Compound Library Gut Microbial Metabolite Library	Click to Expand

Biological Activity

Description

2',3'-Dideoxyadenosine (ddA, ddAdo) is an anti-human immunodeficiency virus agent against human immunodeficiency virus (HIV) and human hepatitis B virus (HBV) replication.

Targets

HIV ^[1]

HBV ^[1]

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06405386	Not yet recruiting	Diabetes type1\|Diabetes Mellitus Type 1\|Diabetes Autoimmune\|Diabetes Mellitus\|Distress Emotional	University of North Carolina Chapel Hill\|American Diabetes Association	May 2024	Not Applicable
NCT06405373	Not yet recruiting	Diabetes type1\|Diabetes Mellitus Type 1\|Diabetes Autoimmune\|Diabetes Mellitus\|Distress Emotional	University of North Carolina Chapel Hill\|American Diabetes Association	May 2024	Not Applicable
NCT05815342	Completed	Type2 Diabetes	Insulet Corporation\|Jaeb Center for Health Research	April 11 2023	Not Applicable
NCT05523362	Completed	Type 2 Diabetes	Ian J. Neeland MD\|DexCom Inc.\|University Hospitals Cleveland Medical Center	January 15 2022	Not Applicable
NCT04821336	Completed	Thyroid Cancer	Institut Claudius Regaud\|Cancer Research Center of Toulouse	April 15 2021	--

References

Chemical Information & Solubility

Molecular Weight	235.24	Formula	C₁₀H₁₃N₅O₂
CAS No.	4097-22-7	SDF	--
Smiles	NC1=C2N=C[N](C3CCC(CO)O3)C2=NC=N1
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 47 mg/mL ( (199.79 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 47 mg/mL

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
=	×	×

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):