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Catalog No. Product Name Information Product Use Citations Product Validations
S7162 Mdivi-1 Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis.
Immunity, 2024, 57(2):287-302.e12
Nat Commun, 2024, 15(1):1669
Autophagy, 2024, 1-22.
S8047 Dynasore Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM in a cell-free assay, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase. Dynasore suppresses mTORC1 activity and induces autophagy. Dynasore inhibits the entry of several viruses, including herpes simplex virus (HSV).
Immunity, 2024, 57(2):287-302.e12
Nat Commun, 2024, 15(1):1669
Redox Biol, 2024, 76:103335
S7163 Dyngo-4a Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1 μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively.
Immunity, 2024, 57(2):287-302.e12
J Extracell Vesicles, 2024, 13(7):e12494
J Colloid Interface Sci, 2024, 664:338-348
S9887 P110 P110 is a dynamin-related protein 1 (Drp1)-specific inhibitor that binds directly to Drp1.
Cell, 2024, S0092-8674(24)00638-X
Cell Mol Biol Lett, 2024, 29(1):31
E1432 TPH104m TPH104m is a thienopyrimidine-hydrazinyl analog that inhibits Drp1 phosphorylation and induces non-apoptotic TNBC cell death. It also significantly inhibits TNBC proliferation.
E1081 MiTMAB

MiTMAB is a selective dynamin inhibitor that targets the dynamin-phospholipid interaction. MiTMAB inhibits dynamin GTPase activity with a Ki of 940 nM.
S5422 Trimethyloctadecylammonium bromide Trimethyloctadecylammonium bromide (Octadecyltrimethylammonium bromide, OcTMAB, C18TAB) is a Dynamin I inhibitor with an IC50 of 1.9 μM and also inhibits Dynamin Ⅱ.
S7162 Mdivi-1 Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis.
Immunity, 2024, 57(2):287-302.e12
Nat Commun, 2024, 15(1):1669
Autophagy, 2024, 1-22.
S8047 Dynasore Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM in a cell-free assay, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase. Dynasore suppresses mTORC1 activity and induces autophagy. Dynasore inhibits the entry of several viruses, including herpes simplex virus (HSV).
Immunity, 2024, 57(2):287-302.e12
Nat Commun, 2024, 15(1):1669
Redox Biol, 2024, 76:103335
S7163 Dyngo-4a Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1 μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively.
Immunity, 2024, 57(2):287-302.e12
J Extracell Vesicles, 2024, 13(7):e12494
J Colloid Interface Sci, 2024, 664:338-348
S9887 P110 P110 is a dynamin-related protein 1 (Drp1)-specific inhibitor that binds directly to Drp1.
Cell, 2024, S0092-8674(24)00638-X
Cell Mol Biol Lett, 2024, 29(1):31
E1432 TPH104m TPH104m is a thienopyrimidine-hydrazinyl analog that inhibits Drp1 phosphorylation and induces non-apoptotic TNBC cell death. It also significantly inhibits TNBC proliferation.
E1081 MiTMAB

MiTMAB is a selective dynamin inhibitor that targets the dynamin-phospholipid interaction. MiTMAB inhibits dynamin GTPase activity with a Ki of 940 nM.
S5422 Trimethyloctadecylammonium bromide Trimethyloctadecylammonium bromide (Octadecyltrimethylammonium bromide, OcTMAB, C18TAB) is a Dynamin I inhibitor with an IC50 of 1.9 μM and also inhibits Dynamin Ⅱ.

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