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RAD51

RAD51 Products

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Catalog No. Product Name Information Product Use Citations Product Validations
S2871 T0070907 T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.
Immunity, 2024, 57(10):2344-2361.e7
Nat Commun, 2024, 15(1):1429
Bone Res, 2024, 12(1):15
S1244 Amuvatinib (MP-470) Amuvatinib (MP-470, HPK 56) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. Amuvatinib suppresses c-MET and c-RET. Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity. Phase 2.
bioRxiv, 2024, 2023.11.21.568071
Microbiol Spectr, 2023, e0510522.
J Pers Med, 2022, 12(2)258
S8077 RI-1 RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.
Int J Mol Sci, 2023, 24(3)2498
Int J Mol Sci, 2023, 24(3)2498
Biomed Rep, 2023, 18(4):28
S8234 RS-1 RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer that enhances Cas9- and TALEN-mediated knock-in efficiency in rabbit embryos both in vitro and in vivo.
J Biomed Sci, 2024, 31(1):68
Int J Biol Sci, 2021, 17(4):1026-1040
Chembiochem, 2021, 22(20):2957-2965
S2871 T0070907 T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.
Immunity, 2024, 57(10):2344-2361.e7
Nat Commun, 2024, 15(1):1429
Bone Res, 2024, 12(1):15
S1244 Amuvatinib (MP-470) Amuvatinib (MP-470, HPK 56) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. Amuvatinib suppresses c-MET and c-RET. Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity. Phase 2.
bioRxiv, 2024, 2023.11.21.568071
Microbiol Spectr, 2023, e0510522.
J Pers Med, 2022, 12(2)258
S8077 RI-1 RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.
Int J Mol Sci, 2023, 24(3)2498
Int J Mol Sci, 2023, 24(3)2498
Biomed Rep, 2023, 18(4):28
S8234 RS-1 RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer that enhances Cas9- and TALEN-mediated knock-in efficiency in rabbit embryos both in vitro and in vivo.
J Biomed Sci, 2024, 31(1):68
Int J Biol Sci, 2021, 17(4):1026-1040
Chembiochem, 2021, 22(20):2957-2965

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Tags: RAD51 inhibitor | RAD51 activator | RAD51 modulator