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TpoR

TpoR Products

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  • TpoR Activators (2)
  • TpoR Agonists (4)
  • New TpoR Products
Catalog No. Product Name Information Product Use Citations Product Validations
S2229 Eltrombopag Olamine Eltrombopag Olamine is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR).
J Transl Med, 2025, 23(1):69
J Mol Cell Biol, 2023, 15(3)mjad017
J Pers Med, 2022, 12(2)258
S4502 Eltrombopag Eltrombopag (SB-497115), a member of the biarylhydrazone class, is a nonpeptide agonist of the thrombopoietin receptor (TpoR), used to treat chronic hepatitis C-associated thrombocytopenia and chronic immune (idiopathic) thrombocytopenia (ITP).
BMC Biol, 2025, 23(1):24
Hemasphere, 2023, 7(6):e906
Am J Cancer Res, 2022, 12(6):2697-2710
S6624 Avatrombopag Avatrombopag (AKR-501,E5501,YM477) is an orally administered, small-molecule thrombopoietin receptor (c-Mpl) agonist which increases platelet number, but not platelet activation.
Cell Death Dis, 2024, 15(12):932
E1352 Butyzamide Butyzamide is a non-peptidyl thrombopoietin receptor, activator of Mpl . It also augments the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. It has potential for treatment of thrombocytopenia.
E4969New Avatrombopag hydrochloride Avatrombopag hydrochloride(AKR-501 hydrochloride, YM477 hydrochloride) is an orally administered second generation agonist of Thrombopoietin receptor(TpoR) with an EC50 value of 3.3 nM. It is used in the treatment of primary chronic immune thrombocytopenia (ITP).
S6988 Lusutrombopag Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist being developed for chronic liver disease (CLD).
S4502 Eltrombopag Eltrombopag (SB-497115), a member of the biarylhydrazone class, is a nonpeptide agonist of the thrombopoietin receptor (TpoR), used to treat chronic hepatitis C-associated thrombocytopenia and chronic immune (idiopathic) thrombocytopenia (ITP).
BMC Biol, 2025, 23(1):24
Hemasphere, 2023, 7(6):e906
Am J Cancer Res, 2022, 12(6):2697-2710
E1352 Butyzamide Butyzamide is a non-peptidyl thrombopoietin receptor, activator of Mpl . It also augments the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. It has potential for treatment of thrombocytopenia.
S2229 Eltrombopag Olamine Eltrombopag Olamine is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR).
J Transl Med, 2025, 23(1):69
J Mol Cell Biol, 2023, 15(3)mjad017
J Pers Med, 2022, 12(2)258
S6624 Avatrombopag Avatrombopag (AKR-501,E5501,YM477) is an orally administered, small-molecule thrombopoietin receptor (c-Mpl) agonist which increases platelet number, but not platelet activation.
Cell Death Dis, 2024, 15(12):932
E4969New Avatrombopag hydrochloride Avatrombopag hydrochloride(AKR-501 hydrochloride, YM477 hydrochloride) is an orally administered second generation agonist of Thrombopoietin receptor(TpoR) with an EC50 value of 3.3 nM. It is used in the treatment of primary chronic immune thrombocytopenia (ITP).
S6988 Lusutrombopag Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist being developed for chronic liver disease (CLD).
E4969New Avatrombopag hydrochloride Avatrombopag hydrochloride(AKR-501 hydrochloride, YM477 hydrochloride) is an orally administered second generation agonist of Thrombopoietin receptor(TpoR) with an EC50 value of 3.3 nM. It is used in the treatment of primary chronic immune thrombocytopenia (ITP).

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