Home Neuronal Signaling AChR inhibitor - BChE inhibitor Vasicine (hydrochloride) For research use only.

Vasicine (hydrochloride)

Synonyms: Peganine hydrochloride

Vasicine hydrochloride(Peganine hydrochloride) is a salt of vasicine (VAS), an alkaloid isolated from Adhatoda vasica, is a potential natural cholinesterase inhibitor. VAS inhibits both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).

Vasicine (hydrochloride) Chemical Structure

Vasicine (hydrochloride) Chemical Structure

CAS No. 7174-27-8

Purity & Quality Control

Batch: E223701 DMSO]45 mg/mL]false]Water]45 mg/mL]false]Ethanol]45 mg/mL]false Purity: 99.54%
99.54

Vasicine (hydrochloride) Related Products

Signaling Pathway

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AChR Signaling Pathway

Biological Activity

Description Vasicine hydrochloride(Peganine hydrochloride) is a salt of vasicine (VAS), an alkaloid isolated from Adhatoda vasica, is a potential natural cholinesterase inhibitor. VAS inhibits both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).
Targets
AChE [1] BChE [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05785377 Not yet recruiting
Analgesia
Mansoura University
 December 1 2025 Not Applicable
NCT02861183 Withdrawn
Epicondylitis|Tennis Elbow|Epicondylosis
Anika Therapeutics Inc.
 September 2025 Not Applicable
NCT03520751 Suspended
Charcot-Marie-Tooth Neuropathy Type 1A
Nationwide Children''s Hospital
 April 2025 Phase 1|Phase 2

Chemical Information & Solubility

Molecular Weight 224.69 Formula

C11H12N2O.ClH
CAS No. 7174-27-8 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 45 mg/mL ( (200.27 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 45 mg/mL

Ethanol : 45 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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