Home Biosimilar Antibodies Neuronal Signaling Notch null Tarextumab (Anti-NOTCH3) For research use only.
Not for use in humans.

Tarextumab (Anti-NOTCH3)

Synonyms: OMP 59R5, Anti-Human NOTCH2 Recombinant Antibody, Anti-Human NOTCH 2 Recombinant Antibody

Tarextumab (Anti-NOTCH3) is an anti-Notch2/3 fully human IgG2 monoclonal antibody with anti-tumor activity. MW: 145.5 kD.

Tarextumab (Anti-NOTCH3)

Purity & Quality Control

Batch: Purity: 99% Protein concentration: 7.22mg/ml Endotoxin Level: ＜1EU/mg
99

Choose Selective Notch Inhibitors

Name Citation Notch Others
RO4929097 115 γ secretase,Aβ40
Semagacestat (LY450139) 20 Aβ42,Aβ38,Aβ40
DBZ (Dibenzazepine) 35 γ secretase
LY411575 35 γ secretase
IMR-1A 0
IMR-1 6
FLI-06 12
Crenigacestat (LY3039478) 23
DAPT Aβ
Limantrafin (CB-103)
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Tarextumab (Anti-NOTCH3) is an anti-Notch2/3 fully human IgG2 monoclonal antibody with anti-tumor activity. MW: 145.5 kD.

Product Details

CAS No. 1359940-55-8
Molecular Weight 145.5 kDa
Isotype Human IgG2SA
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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