MV-4-11 |
Growth Inhibition Assay |
|
|
|
IC50=0.00000303 ��M |
SANGER |
MONO-MAC-6 |
Growth Inhibition Assay |
|
|
|
IC50=0.00418 ��M |
SANGER |
ALL-PO |
Growth Inhibition Assay |
|
|
|
IC50=0.03184 ��M |
SANGER |
NKM-1 |
Growth Inhibition Assay |
|
|
|
IC50=0.07416 ��M |
SANGER |
CGTH-W-1 |
Growth Inhibition Assay |
|
|
|
IC50=0.25022 ��M |
SANGER |
BB65-RCC |
Growth Inhibition Assay |
|
|
|
IC50=0.47073 ��M |
SANGER |
NOS-1 |
Growth Inhibition Assay |
|
|
|
IC50=0.5636 ��M |
SANGER |
SH-4 |
Growth Inhibition Assay |
|
|
|
IC50=0.65613 ��M |
SANGER |
HOP-62 |
Growth Inhibition Assay |
|
|
|
IC50=0.85088 ��M |
SANGER |
HCC2998 |
Growth Inhibition Assay |
|
|
|
IC50=0.88818 ��M |
SANGER |
GDM-1 |
Growth Inhibition Assay |
|
|
|
IC50=0.90698 ��M |
SANGER |
KM12 |
Growth Inhibition Assay |
|
|
|
IC50=1.02098 ��M |
SANGER |
LB2518-MEL |
Growth Inhibition Assay |
|
|
|
IC50=1.20809 ��M |
SANGER |
NCI-H1436 |
Growth Inhibition Assay |
|
|
|
IC50=1.21678 ��M |
SANGER |
EM-2 |
Growth Inhibition Assay |
|
|
|
IC50=1.35578 ��M |
SANGER |
LAMA-84 |
Growth Inhibition Assay |
|
|
|
IC50=1.37648 ��M |
SANGER |
KG-1 |
Growth Inhibition Assay |
|
|
|
IC50=1.47935 ��M |
SANGER |
A388 |
Growth Inhibition Assay |
|
|
|
IC50=1.59165 ��M |
SANGER |
no-10 |
Growth Inhibition Assay |
|
|
|
IC50=1.61726 ��M |
SANGER |
SF126 |
Growth Inhibition Assay |
|
|
|
IC50=1.63812 ��M |
SANGER |
MEG-01 |
Growth Inhibition Assay |
|
|
|
IC50=1.8098 ��M |
SANGER |
A3-KAW |
Growth Inhibition Assay |
|
|
|
IC50=1.8842 ��M |
SANGER |
D-247MG |
Growth Inhibition Assay |
|
|
|
IC50=2.1448 ��M |
SANGER |
OVCAR-4 |
Growth Inhibition Assay |
|
|
|
IC50=2.21393 ��M |
SANGER |
NCI-SNU-1 |
Growth Inhibition Assay |
|
|
|
IC50=2.3162 ��M |
SANGER |
NCI-H2171 |
Growth Inhibition Assay |
|
|
|
IC50=2.39764 ��M |
SANGER |
SIG-M5 |
Growth Inhibition Assay |
|
|
|
IC50=2.42242 ��M |
SANGER |
BE-13 |
Growth Inhibition Assay |
|
|
|
IC50=2.69609 ��M |
SANGER |
K052 |
Growth Inhibition Assay |
|
|
|
IC50=2.74616 ��M |
SANGER |
L-540 |
Growth Inhibition Assay |
|
|
|
IC50=2.75789 ��M |
SANGER |
KMOE-2 |
Growth Inhibition Assay |
|
|
|
IC50=2.8135 ��M |
SANGER |
MFH-ino |
Growth Inhibition Assay |
|
|
|
IC50=2.92185 ��M |
SANGER |
HL-60 |
Growth Inhibition Assay |
|
|
|
IC50=3.06299 ��M |
SANGER |
HCC2218 |
Growth Inhibition Assay |
|
|
|
IC50=3.12003 ��M |
SANGER |
TE-5 |
Growth Inhibition Assay |
|
|
|
IC50=3.13162 ��M |
SANGER |
MZ1-PC |
Growth Inhibition Assay |
|
|
|
IC50=3.47509 ��M |
SANGER |
MRK-nu-1 |
Growth Inhibition Assay |
|
|
|
IC50=3.61468 ��M |
SANGER |
MZ7-mel |
Growth Inhibition Assay |
|
|
|
IC50=3.66099 ��M |
SANGER |
BC-1 |
Growth Inhibition Assay |
|
|
|
IC50=3.7402 ��M |
SANGER |
ST486 |
Growth Inhibition Assay |
|
|
|
IC50=3.83673 ��M |
SANGER |
KS-1 |
Growth Inhibition Assay |
|
|
|
IC50=3.88198 ��M |
SANGER |
SK-NEP-1 |
Growth Inhibition Assay |
|
|
|
IC50=4.16815 ��M |
SANGER |
BC-3 |
Growth Inhibition Assay |
|
|
|
IC50=4.23391 ��M |
SANGER |
NCI-H1581 |
Growth Inhibition Assay |
|
|
|
IC50=4.28798 ��M |
SANGER |
MHH-PREB-1 |
Growth Inhibition Assay |
|
|
|
IC50=4.40484 ��M |
SANGER |
NOMO-1 |
Growth Inhibition Assay |
|
|
|
IC50=4.48905 ��M |
SANGER |
QIMR-WIL |
Growth Inhibition Assay |
|
|
|
IC50=5.07294 ��M |
SANGER |
SF539 |
Growth Inhibition Assay |
|
|
|
IC50=5.13227 ��M |
SANGER |
TE-12 |
Growth Inhibition Assay |
|
|
|
IC50=5.24929 ��M |
SANGER |
NCI-H510A |
Growth Inhibition Assay |
|
|
|
IC50=5.41685 ��M |
SANGER |
JAR |
Growth Inhibition Assay |
|
|
|
IC50=5.50824 ��M |
SANGER |
no-11 |
Growth Inhibition Assay |
|
|
|
IC50=5.73568 ��M |
SANGER |
BV-173 |
Growth Inhibition Assay |
|
|
|
IC50=5.95682 ��M |
SANGER |
SR |
Growth Inhibition Assay |
|
|
|
IC50=6.00678 ��M |
SANGER |
MOLT-16 |
Growth Inhibition Assay |
|
|
|
IC50=6.25266 ��M |
SANGER |
MZ2-MEL |
Growth Inhibition Assay |
|
|
|
IC50=6.31839 ��M |
SANGER |
SW954 |
Growth Inhibition Assay |
|
|
|
IC50=6.45866 ��M |
SANGER |
ML-2 |
Growth Inhibition Assay |
|
|
|
IC50=6.52849 ��M |
SANGER |
OCI-AML2 |
Growth Inhibition Assay |
|
|
|
IC50=6.61062 ��M |
SANGER |
SIMA |
Growth Inhibition Assay |
|
|
|
IC50=7.00101 ��M |
SANGER |
DOHH-2 |
Growth Inhibition Assay |
|
|
|
IC50=7.05676 ��M |
SANGER |
697 |
Growth Inhibition Assay |
|
|
|
IC50=7.05989 ��M |
SANGER |
NB1 |
Growth Inhibition Assay |
|
|
|
IC50=7.40407 ��M |
SANGER |
D-392MG |
Growth Inhibition Assay |
|
|
|
IC50=7.62663 ��M |
SANGER |
ES8 |
Growth Inhibition Assay |
|
|
|
IC50=7.76503 ��M |
SANGER |
RPMI-8226 |
Growth Inhibition Assay |
|
|
|
IC50=7.84511 ��M |
SANGER |
IST-MEL1 |
Growth Inhibition Assay |
|
|
|
IC50=8.40002 ��M |
SANGER |
NB14 |
Growth Inhibition Assay |
|
|
|
IC50=8.63133 ��M |
SANGER |
HD-MY-Z |
Growth Inhibition Assay |
|
|
|
IC50=8.63746 ��M |
SANGER |
TE-10 |
Growth Inhibition Assay |
|
|
|
IC50=8.76353 ��M |
SANGER |
LC-1F |
Growth Inhibition Assay |
|
|
|
IC50=9.10834 ��M |
SANGER |
OS-RC-2 |
Growth Inhibition Assay |
|
|
|
IC50=9.11243 ��M |
SANGER |
NCI-SNU-16 |
Growth Inhibition Assay |
|
|
|
IC50=9.21026 ��M |
SANGER |
SHP-77 |
Growth Inhibition Assay |
|
|
|
IC50=9.71662 ��M |
SANGER |
A4-Fuk |
Growth Inhibition Assay |
|
|
|
IC50=9.7561 ��M |
SANGER |
NB6 |
Growth Inhibition Assay |
|
|
|
IC50=9.76029 ��M |
SANGER |
JiyoyeP-2003 |
Growth Inhibition Assay |
|
|
|
IC50=10.4745 ��M |
SANGER |
DMS-114 |
Growth Inhibition Assay |
|
|
|
IC50=10.5441 ��M |
SANGER |
NB7 |
Growth Inhibition Assay |
|
|
|
IC50=10.7526 ��M |
SANGER |
NCI-H747 |
Growth Inhibition Assay |
|
|
|
IC50=11.1216 ��M |
SANGER |
HH |
Growth Inhibition Assay |
|
|
|
IC50=11.3876 ��M |
SANGER |
EW-18 |
Growth Inhibition Assay |
|
|
|
IC50=11.9044 ��M |
SANGER |
CHP-126 |
Growth Inhibition Assay |
|
|
|
IC50=11.9738 ��M |
SANGER |
NTERA-S-cl-D1 |
Growth Inhibition Assay |
|
|
|
IC50=12.0278 ��M |
SANGER |
DEL |
Growth Inhibition Assay |
|
|
|
IC50=12.0985 ��M |
SANGER |
LU-139 |
Growth Inhibition Assay |
|
|
|
IC50=12.5413 ��M |
SANGER |
P30-OHK |
Growth Inhibition Assay |
|
|
|
IC50=12.5479 ��M |
SANGER |
NCI-H1522 |
Growth Inhibition Assay |
|
|
|
IC50=12.746 ��M |
SANGER |
NCI-H1299 |
Growth Inhibition Assay |
|
|
|
IC50=13.2911 ��M |
SANGER |
UACC-257 |
Growth Inhibition Assay |
|
|
|
IC50=13.5126 ��M |
SANGER |
Calu-6 |
Growth Inhibition Assay |
|
|
|
IC50=13.6046 ��M |
SANGER |
NCI-H1882 |
Growth Inhibition Assay |
|
|
|
IC50=13.8555 ��M |
SANGER |
BB30-HNC |
Growth Inhibition Assay |
|
|
|
IC50=14.0609 ��M |
SANGER |
ES1 |
Growth Inhibition Assay |
|
|
|
IC50=14.1551 ��M |
SANGER |
NCI-H1694 |
Growth Inhibition Assay |
|
|
|
IC50=14.4811 ��M |
SANGER |
IST-SL1 |
Growth Inhibition Assay |
|
|
|
IC50=14.9616 ��M |
SANGER |
ECC4 |
Growth Inhibition Assay |
|
|
|
IC50=15.0558 ��M |
SANGER |
MDA-MB-134-VI |
Growth Inhibition Assay |
|
|
|
IC50=15.4131 ��M |
SANGER |
SCH |
Growth Inhibition Assay |
|
|
|
IC50=15.4728 ��M |
SANGER |
SK-N-FI |
Growth Inhibition Assay |
|
|
|
IC50=15.6534 ��M |
SANGER |
HDLM-2 |
Growth Inhibition Assay |
|
|
|
IC50=16.0714 ��M |
SANGER |
Ramos-2G6-4C10 |
Growth Inhibition Assay |
|
|
|
IC50=16.1297 ��M |
SANGER |
EW-24 |
Growth Inhibition Assay |
|
|
|
IC50=16.1661 ��M |
SANGER |
NCI-H2141 |
Growth Inhibition Assay |
|
|
|
IC50=16.189 ��M |
SANGER |
LC4-1 |
Growth Inhibition Assay |
|
|
|
IC50=16.6119 ��M |
SANGER |
HT-144 |
Growth Inhibition Assay |
|
|
|
IC50=17.006 ��M |
SANGER |
SK-MEL-1 |
Growth Inhibition Assay |
|
|
|
IC50=17.0072 ��M |
SANGER |
SCC-15 |
Growth Inhibition Assay |
|
|
|
IC50=17.1638 ��M |
SANGER |
C8166 |
Growth Inhibition Assay |
|
|
|
IC50=17.6833 ��M |
SANGER |
GOTO |
Growth Inhibition Assay |
|
|
|
IC50=17.8344 ��M |
SANGER |
COR-L279 |
Growth Inhibition Assay |
|
|
|
IC50=18.1362 ��M |
SANGER |
K-562 |
Growth Inhibition Assay |
|
|
|
IC50=18.7143 ��M |
SANGER |
ES3 |
Growth Inhibition Assay |
|
|
|
IC50=18.8041 ��M |
SANGER |
LU-165 |
Growth Inhibition Assay |
|
|
|
IC50=19.7008 ��M |
SANGER |
KM-H2 |
Growth Inhibition Assay |
|
|
|
IC50=20.3184 ��M |
SANGER |
RL |
Growth Inhibition Assay |
|
|
|
IC50=20.9692 ��M |
SANGER |
EW-3 |
Growth Inhibition Assay |
|
|
|
IC50=21.1889 ��M |
SANGER |
A101D |
Growth Inhibition Assay |
|
|
|
IC50=21.3752 ��M |
SANGER |
HUTU-80 |
Growth Inhibition Assay |
|
|
|
IC50=21.3946 ��M |
SANGER |
NCI-H23 |
Growth Inhibition Assay |
|
|
|
IC50=21.3992 ��M |
SANGER |
PF-382 |
Growth Inhibition Assay |
|
|
|
IC50=21.4403 ��M |
SANGER |
LB373-MEL-D |
Growth Inhibition Assay |
|
|
|
IC50=21.5615 ��M |
SANGER |
TE-8 |
Growth Inhibition Assay |
|
|
|
IC50=21.6394 ��M |
SANGER |
TE-9 |
Growth Inhibition Assay |
|
|
|
IC50=21.8513 ��M |
SANGER |
Daudi |
Growth Inhibition Assay |
|
|
|
IC50=21.9304 ��M |
SANGER |
D-542MG |
Growth Inhibition Assay |
|
|
|
IC50=22.0256 ��M |
SANGER |
U-698-M |
Growth Inhibition Assay |
|
|
|
IC50=22.4603 ��M |
SANGER |
ES6 |
Growth Inhibition Assay |
|
|
|
IC50=22.7366 ��M |
SANGER |
DU-4475 |
Growth Inhibition Assay |
|
|
|
IC50=23.8897 ��M |
SANGER |
ECC12 |
Growth Inhibition Assay |
|
|
|
IC50=24.2803 ��M |
SANGER |
C2BBe1 |
Growth Inhibition Assay |
|
|
|
IC50=24.3239 ��M |
SANGER |
IST-SL2 |
Growth Inhibition Assay |
|
|
|
IC50=24.4362 ��M |
SANGER |
DJM-1 |
Growth Inhibition Assay |
|
|
|
IC50=24.5221 ��M |
SANGER |
DMS-153 |
Growth Inhibition Assay |
|
|
|
IC50=24.8614 ��M |
SANGER |
NB13 |
Growth Inhibition Assay |
|
|
|
IC50=25.0265 ��M |
SANGER |
SK-N-DZ |
Growth Inhibition Assay |
|
|
|
IC50=26.3414 ��M |
SANGER |
COR-L88 |
Growth Inhibition Assay |
|
|
|
IC50=26.5796 ��M |
SANGER |
LU-65 |
Growth Inhibition Assay |
|
|
|
IC50=26.8535 ��M |
SANGER |
TGBC1TKB |
Growth Inhibition Assay |
|
|
|
IC50=26.9828 ��M |
SANGER |
THP-1 |
Growth Inhibition Assay |
|
|
|
IC50=27.2141 ��M |
SANGER |
ONS-76 |
Growth Inhibition Assay |
|
|
|
IC50=27.332 ��M |
SANGER |
LC-2-ad |
Growth Inhibition Assay |
|
|
|
IC50=27.6231 ��M |
SANGER |
EW-13 |
Growth Inhibition Assay |
|
|
|
IC50=29.1746 ��M |
SANGER |
MS-1 |
Growth Inhibition Assay |
|
|
|
IC50=30.7278 ��M |
SANGER |
NCI-H2227 |
Growth Inhibition Assay |
|
|
|
IC50=30.9806 ��M |
SANGER |
LXF-289 |
Growth Inhibition Assay |
|
|
|
IC50=31.4492 ��M |
SANGER |
MC116 |
Growth Inhibition Assay |
|
|
|
IC50=32.0826 ��M |
SANGER |
EVSA-T |
Growth Inhibition Assay |
|
|
|
IC50=32.2585 ��M |
SANGER |
CTB-1 |
Growth Inhibition Assay |
|
|
|
IC50=33.1101 ��M |
SANGER |
COLO-320-HSR |
Growth Inhibition Assay |
|
|
|
IC50=33.1603 ��M |
SANGER |
NCI-H2196 |
Growth Inhibition Assay |
|
|
|
IC50=33.2557 ��M |
SANGER |
LB2241-RCC |
Growth Inhibition Assay |
|
|
|
IC50=33.3135 ��M |
SANGER |
LS-513 |
Growth Inhibition Assay |
|
|
|
IC50=33.8638 ��M |
SANGER |
LP-1 |
Growth Inhibition Assay |
|
|
|
IC50=33.9956 ��M |
SANGER |
A253 |
Growth Inhibition Assay |
|
|
|
IC50=34.2296 ��M |
SANGER |
SK-MM-2 |
Growth Inhibition Assay |
|
|
|
IC50=34.9451 ��M |
SANGER |
NCI-H1963 |
Growth Inhibition Assay |
|
|
|
IC50=35.3072 ��M |
SANGER |
MMAC-SF |
Growth Inhibition Assay |
|
|
|
IC50=35.8785 ��M |
SANGER |
LB831-BLC |
Growth Inhibition Assay |
|
|
|
IC50=36.0654 ��M |
SANGER |
WSU-NHL |
Growth Inhibition Assay |
|
|
|
IC50=36.164 ��M |
SANGER |
CESS |
Growth Inhibition Assay |
|
|
|
IC50=36.2848 ��M |
SANGER |
NEC8 |
Growth Inhibition Assay |
|
|
|
IC50=36.5835 ��M |
SANGER |
KNS-42 |
Growth Inhibition Assay |
|
|
|
IC50=37.1237 ��M |
SANGER |
MHH-CALL-2 |
Growth Inhibition Assay |
|
|
|
IC50=37.1821 ��M |
SANGER |
K5 |
Growth Inhibition Assay |
|
|
|
IC50=38.43 ��M |
SANGER |
CP66-MEL |
Growth Inhibition Assay |
|
|
|
IC50=39.0733 ��M |
SANGER |
OPM-2 |
Growth Inhibition Assay |
|
|
|
IC50=39.8432 ��M |
SANGER |
IST-MES1 |
Growth Inhibition Assay |
|
|
|
IC50=40.3096 ��M |
SANGER |
EC-GI-10 |
Growth Inhibition Assay |
|
|
|
IC50=41.5805 ��M |
SANGER |
CTV-1 |
Growth Inhibition Assay |
|
|
|
IC50=42.8406 ��M |
SANGER |
DG-75 |
Growth Inhibition Assay |
|
|
|
IC50=43.7595 ��M |
SANGER |
KNS-81-FD |
Growth Inhibition Assay |
|
|
|
IC50=45.4058 ��M |
SANGER |
NCI-H82 |
Growth Inhibition Assay |
|
|
|
IC50=45.5758 ��M |
SANGER |
RPMI-8866 |
Growth Inhibition Assay |
|
|
|
IC50=46.1873 ��M |
SANGER |
ACN |
Growth Inhibition Assay |
|
|
|
IC50=46.434 ��M |
SANGER |
NCI-H1395 |
Growth Inhibition Assay |
|
|
|
IC50=46.4756 ��M |
SANGER |
NCI-H209 |
Growth Inhibition Assay |
|
|
|
IC50=47.1405 ��M |
SANGER |
TGW |
Growth Inhibition Assay |
|
|
|
IC50=49.0791 ��M |
SANGER |
NCI-H748 |
Growth Inhibition Assay |
|
|
|
IC50=49.4753 ��M |
SANGER |
EKVX |
Growth Inhibition Assay |
|
|
|
IC50=49.6628 ��M |
SANGER |
MV4-11 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.00087 ��M |
19754199 |
MV4-11 |
Cytotoxicity assay |
|
|
|
IC50 = 0.00087 ��M |
19654408 |
TT |
Antiproliferative activity assay |
|
|
|
IC50 = 0.0014 ��M |
18849971 |
RS4-11 |
Function assay |
|
|
|
IC50 = 0.002 ��M |
19654408 |
MOLM13 |
Function assay |
|
|
|
IC50 = 0.002 ��M |
24641103 |
Sf9 |
Function assay |
|
|
|
IC50 = 0.003 ��M |
21708468 |
RS4-11 |
Function assay |
|
|
|
IC50 = 0.0032 ��M |
19654408 |
MV4-11 |
Growth inhibition assay |
|
|
|
IC50 = 0.004 ��M |
29357250 |
A375 |
Function assay |
|
|
|
IC50 = 0.0044 ��M |
29461827 |
MOLM13 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.005 ��M |
24641103 |
MV4-11 |
Function assay |
|
|
|
IC50 = 0.007 ��M |
23362959 |
MV4-11 |
Cytotoxicity assay |
|
|
|
IC50 = 0.007 ��M |
26342867 |
HEK293 |
Function assay |
|
|
|
Kd = 0.013 ��M |
19754199 |
Kasumi-1 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.015 ��M |
20570526 |
MV4-11 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.015 ��M |
20570526 |
sf9 |
Function assay |
|
|
|
IC50 = 0.015 ��M |
29266937 |
sf9 |
Function assay |
|
|
|
IC50 = 0.018 ��M |
21708468 |
sf9 |
Function assay |
|
|
|
IC50 = 0.02 ��M |
23618709 |
MV4-11 |
Antiproliferative activity assay |
|
|
|
GI50 = 0.03 ��M |
21708468 |
Sf9 |
Function assay |
|
|
|
IC50 = 0.042 ��M |
26081023 |
SF9 |
Function assay |
|
|
|
IC50 = 0.043 ��M |
18473434 |
MV4-11 |
Cytotoxicity assay |
|
|
|
GI50 = 0.043 ��M |
23618709 |
MV4-11 |
Function assay |
|
|
|
GI50 = 0.043 ��M |
26081023 |
SF9 |
Function assay |
|
|
|
IC50 = 0.044 ��M |
26081023 |
SF9 |
Function assay |
|
|
|
IC50 = 0.054 ��M |
21708468 |
SF9 |
Function assay |
|
|
|
IC50 = 0.054 ��M |
23618709 |
MOLM13 |
Antiproliferative activity assay |
|
|
|
GI50 = 0.056 ��M |
21708468 |
MOLM13 |
Antiproliferative activity assay |
|
|
|
GI50 = 0.056 ��M |
22726931 |
MOLM13 |
Cytotoxicity assay |
|
|
|
GI50 = 0.056 ��M |
23618709 |
MOLM-13 |
Function assay |
|
|
|
GI50 = 0.056 ��M |
26081023 |
SF9 |
Function assay |
|
|
|
IC50 = 0.058 ��M |
29266937 |
WM266.4 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.06 ��M |
25496804 |
MDA-MB-231 |
Function assay |
|
|
|
IC50 = 0.063 ��M |
28431342 |
SF9 |
Function assay |
|
|
|
IC50 = 0.09 ��M |
29266937 |
Spodoptera frugiperda |
Function assay |
|
|
|
IC50 = 0.09 ��M |
26922228 |
SF9 |
Function assay |
|
|
|
IC50 = 0.09 ��M |
23562241 |
SF9 |
Function assay |
|
|
|
IC50 = 0.1 ��M |
23442188 |
SF9 |
Function assay |
|
|
|
IC50 = 0.1 ��M |
23442188 |
HEK293 |
Function assay |
|
|
|
IC50 = 0.12 ��M |
26318998 |
MCF7 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.19 ��M |
25496804 |
MV4-11 |
Antiproliferative activity human |
|
|
|
IC50 = 0.3 ��M |
28242553 |
HepG2 |
Antiproliferative activity assay |
|
|
|
EC50 = 0.302 ��M |
27010810 |
THP1 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.31 ��M |
20570526 |
SMMC7721 |
Cytotoxicity assay |
|
|
|
IC50 = 0.37 ��M |
25982075 |
HT-29 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.39 ��M |
25778995 |
sf9 |
Function assay |
|
|
|
Kd = 0.6 ��M |
28109791 |
T47D |
Antiproliferative activity assay |
|
|
|
IC50 = 0.61 ��M |
25778995 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 0.63 ��M |
25982075 |
HeLa |
Cytotoxicity assay |
|
|
|
IC50 = 0.64 ��M |
30015070 |
WM3629 |
Antiproliferative activity assay |
|
|
|
GI50 = 0.65 ��M |
20466542 |
SMMC7721 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.65 ��M |
26342134 |
WM3629 |
Growth inhibition assay |
|
|
|
GI50 = 0.78 ��M |
20149658 |
WM3629 |
Antiproliferative activity assay |
|
|
|
GI50 = 0.78 ��M |
26810260 |
MCF7 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.78 ��M |
25778995 |
K562 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.86 ��M |
24315192 |
COLO205 |
Antiproliferative activity assay |
|
|
|
IC50 = 0.87 ��M |
25778995 |
T29 |
Cytotoxicity assay |
|
|
|
IC50 = 0.9 ��M |
26318998 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
|
IC50 = 0.94 ��M |
25086238 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
|
IC50 = 0.94 ��M |
25440879 |
HepG2 |
Antiproliferative activity assay |
|
|
|
IC50 = 1.06 ��M |
29628325 |
BL21(DE3) |
Function assay |
|
|
|
IC50 = 1.1 ��M |
19928858 |
K562 |
Antiproliferative activity assay |
|
|
|
IC50 = 1.22 ��M |
25778995 |
MDA-MB-231 |
Growth inhibition assay |
|
|
|
GI50 = 1.26 ��M |
28088086 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
|
GI50 = 1.26 ��M |
26590508 |
MDA-MB-231 |
Antiproliferative activity assay |
|
|
|
GI50 = 1.26 ��M |
27017549 |
SK-MEL-28 |
Antiproliferative activity assay |
|
|
|
EC50 = 1.3 ��M |
18942827 |
sf9 |
Function assay |
|
|
|
Kd = 1.3 ��M |
28109791 |
F-6-8 |
Cytotoxicity assay |
|
|
|
IC50 = 1.3 ��M |
26318998 |
A549 |
Antiproliferative activity assay |
|
|
|
IC50 = 1.45 ��M |
26342134 |
rhabdomyosarcoma |
Antiviral activity assay |
|
|
|
EC50 = 1.5 ��M |
27288186 |
HL-60(TB) |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
RPMI8226 |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
KM12 |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
LOXIMVI |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
HCT116 |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
HOP92 |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
SF539 |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
UACC62 |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
SF295 |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
MDA-MB-435 |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
SK-MEL-5 |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
T47D |
Growth inhibition assay |
|
|
|
GI50 = 1.58 ��M |
28088086 |
RPMI8266 |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
HL-60(TB) |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
KM12 |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
HCT116 |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
SF295 |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
SF539 |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
SK-MEL-2 |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
MDA-MB-435 |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
SK-MEL-5 |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
LOXIMVI |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
T47D |
Cytotoxicity assay |
|
|
|
GI50 = 1.58 ��M |
26590508 |
SMMC7721 |
Antiproliferative activity assay |
|
|
|
IC50 = 1.58 ��M |
26753815 |
LOXIMVI |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
UACC62 |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
SK-MEL-5 |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
KM12 |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
MDA-MB-435 |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
SF539 |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
SF295 |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
HCT116 |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
HOP92 |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
RPMI8226 |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
HL-60(TB) |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
T47D |
Antiproliferative activity assay |
|
|
|
GI50 = 1.58 ��M |
27017549 |
7dF3 |
Function assay |
|
|
|
IC50 = 1.62 ��M |
29266937 |
MDA-MB-435 |
Antiproliferative activity assay |
|
|
|
IC50 = 1.67 ��M |
25778995 |
HL60 |
Cytotoxicity assay |
|
|
|
IC50 = 1.68 ��M |
24858546 |
SW579 |
Antiproliferative activity human |
|
|
|
IC50 = 1.73 ��M |
28242553 |
MCF7 |
Antiproliferative activity assay |
|
|
|
IC50 = 1.88 ��M |
25637123 |
A375P |
Antiproliferative activity assay |
|
|
|
IC50 = 1.9 ��M |
24128410 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 1.92 ��M |
24826815 |
HCT116 |
Antiproliferative activity assay |
|
|
|
IC50 = 2 ��M |
22808911 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
|
IC50 = 2 ��M |
23454017 |
NCI-H23 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
NCI-H522 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
HOP62 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
NCI-H226 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
HT-29 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
U251 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
COLO205 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
CCRF-CEM |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
MALME-3M |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
M14 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
UACC257 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
PC3 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
SK-MEL-2 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
MDA-MB-468 |
Growth inhibition assay |
|
|
|
GI50 = 2 ��M |
28088086 |
CCRF-CEM |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
NCI-H23 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
NCI-H522 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
COLO205 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
HT-29 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
SK-MEL-28 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
HOP62 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
UACC257 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
NCI-H226 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
U251 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
PC3 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
M14 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
MDA-MB-468 |
Cytotoxicity assay |
|
|
|
GI50 = 2 ��M |
26590508 |
PC3 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
MALME-3M |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
U251 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
UACC257 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
SK-MEL-2 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
COLO205 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
NCI-H23 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
HT-29 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
M14 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
NCI-H226 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
HOP62 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
MDA-MB-468 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
CCRF-CEM |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
NCI-H522 |
Antiproliferative activity assay |
|
|
|
GI50 = 2 ��M |
27017549 |
A549 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.02 ��M |
26753815 |
MDA-MB-435 |
Growth inhibition assay |
|
|
|
IC50 = 2.11 ��M |
29189002 |
NCI-H460 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.19 ��M |
30216849 |
H460 |
Cytotoxicity assay |
|
|
|
IC50 = 2.19 ��M |
24826815 |
H460 |
Cytotoxicity assay |
|
|
|
IC50 = 2.19 ��M |
25086238 |
H460 |
Cytotoxicity assay |
|
|
|
IC50 = 2.19 ��M |
25440879 |
A375 |
Toxicity assay |
|
|
|
IC50 = 2.2 ��M |
19654408 |
H460 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.25 ��M |
26991938 |
HCT116 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.3 ��M |
23260578 |
MKN45 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.32 ��M |
30216849 |
MKN45 |
Cytotoxicity assay |
|
|
|
IC50 = 2.32 ��M |
24826815 |
MKN45 |
Cytotoxicity assay |
|
|
|
IC50 = 2.32 ��M |
25086238 |
MKN45 |
Cytotoxicity assay |
|
|
|
IC50 = 2.32 ��M |
25440879 |
U937 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.34 ��M |
29459144 |
A375 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.4 ��M |
22808911 |
HeLa |
Growth inhibition assay |
|
|
|
IC50 = 2.44 ��M |
29102175 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
|
IC50 = 2.5 ��M |
22414612 |
MCF7 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.51 ��M |
30216849 |
UO31 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.51 ��M |
30216849 |
NCI-H322M |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
NCI-H460 |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
KM12 |
Growth inhibition assay |
|
|
|
TGI = 2.51 ��M |
28088086 |
LOXIMVI |
Growth inhibition assay |
|
|
|
TGI = 2.51 ��M |
28088086 |
EKVX |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
HCT116 |
Growth inhibition assay |
|
|
|
TGI = 2.51 ��M |
28088086 |
SW620 |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
SF268 |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
SF539 |
Growth inhibition assay |
|
|
|
TGI = 2.51 ��M |
28088086 |
A498 |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
UACC62 |
Growth inhibition assay |
|
|
|
TGI = 2.51 ��M |
28088086 |
IGROV1 |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
HCT15 |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
SK-MEL-28 |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
SK-MEL-28 |
Growth inhibition assay |
|
|
|
TGI = 2.51 ��M |
28088086 |
ACHN |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
SK-MEL-5 |
Growth inhibition assay |
|
|
|
TGI = 2.51 ��M |
28088086 |
NCI/ADR-RES |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
MCF7 |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
SN12C |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
Hs 578T |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
SKOV3 |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
UO31 |
Growth inhibition assay |
|
|
|
GI50 = 2.51 ��M |
28088086 |
NCI-H460 |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
HCT15 |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
SW620 |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
SF268 |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
IGROV1 |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
OVCAR8 |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
NCI/ADR-RES |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
SKOV3 |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
SN12C |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
NCI-H322M |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
MCF7 |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
UO31 |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
Hs578T |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
A498 |
Cytotoxicity assay |
|
|
|
GI50 = 2.51 ��M |
26590508 |
A498 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
SKOV3 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
UO31 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
NCI-ADR-RES |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
SN12C |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
IGROV1 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
ACHN |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
OVCAR8 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
SK-MEL-28 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
NCI-H322M |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
SF268 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
HCT15 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
NCI-H460 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
SW620 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
EKVX |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
MCF7 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
Hs 578T |
Antiproliferative activity assay |
|
|
|
GI50 = 2.51 ��M |
27017549 |
HT-29 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.58 ��M |
29886324 |
A375P |
Antiproliferative activity assay |
|
|
|
GI50 = 2.58 ��M |
26810260 |
TPC1 |
Antiproliferative activity assay |
|
|
|
EC50 = 2.6 ��M |
22559926 |
Hep3B |
Growth inhibition assay |
|
|
|
IC50 = 2.63 ��M |
29102175 |
A375P |
Antiproliferative activity assay |
|
|
|
IC50 = 2.7 ��M |
22460030 |
U937 |
Antiproliferative activity assay |
|
|
|
GI50 = 2.74 ��M |
26318067 |
U937 |
Cytotoxicity assay |
|
|
|
GI50 = 2.74 ��M |
24878193 |
MCF7 |
Growth inhibition assay |
|
|
|
IC50 = 2.78 ��M |
29102175 |
MDA-MB-231 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.8 ��M |
29202403 |
HepG2 |
Antiproliferative activity assay |
|
|
|
IC50 = 2.84 ��M |
28242553 |
U937 |
Growth inhibition assay |
|
|
|
GI50 = 2.85 ��M |
22014755 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 2.92 ��M |
28927801 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 2.92 ��M |
27777009 |
ZR75-30 |
Growth inhibition assay |
|
|
|
IC50 = 2.96 ��M |
29102175 |
PC3 |
Cytotoxicity assay |
|
|
|
IC50 = 3.03 ��M |
28340913 |
MDA-MB-231 |
Antiproliferative activity assay |
|
|
|
IC50 = 3.08 ��M |
26991938 |
A549 |
Growth inhibition assay |
|
|
|
IC50 = 3.1 ��M |
29102175 |
K562 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
MOLT4 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
A549/ATCC |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
RPMI8226 |
Growth inhibition assay |
|
|
|
TGI = 3.16 ��M |
28088086 |
SR |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
HOP62 |
Growth inhibition assay |
|
|
|
TGI = 3.16 ��M |
28088086 |
NCI-H226 |
Growth inhibition assay |
|
|
|
TGI = 3.16 ��M |
28088086 |
U251 |
Growth inhibition assay |
|
|
|
TGI = 3.16 ��M |
28088086 |
COLO205 |
Growth inhibition assay |
|
|
|
TGI = 3.16 ��M |
28088086 |
M14 |
Growth inhibition assay |
|
|
|
TGI = 3.16 ��M |
28088086 |
HCC2998 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
SNB75 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
786-0 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
A498 |
Growth inhibition assay |
|
|
|
TGI = 3.16 ��M |
28088086 |
HCT15 |
Growth inhibition assay |
|
|
|
TGI = 3.16 ��M |
28088086 |
OVCAR3 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
OVCAR4 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
Caki1 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
SNB19 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
OVCAR5 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
DU145 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
OVCAR8 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
SN12C |
Growth inhibition assay |
|
|
|
TGI = 3.16 ��M |
28088086 |
MDA-MB-231 |
Growth inhibition assay |
|
|
|
TGI = 3.16 ��M |
28088086 |
RXF393 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
BT549 |
Growth inhibition assay |
|
|
|
GI50 = 3.16 ��M |
28088086 |
K562 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
MOLT4 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
SNB19 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
SR |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
A549 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
OVCAR3 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
OVCAR4 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
SNB75 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
OVCAR5 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
DU145 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
786-0 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
BT549 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
ACHN |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
Caki1 |
Cytotoxicity assay |
|
|
|
GI50 = 3.16 ��M |
26590508 |
786-0 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
LOXIMVI |
Antiproliferative activity assay |
|
|
|
TGI = 3.16 ��M |
27017549 |
Caki1 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
OVCAR5 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
RXF393 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
SNB75 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
OVCAR3 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
SNB19 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
SK-MEL-5 |
Antiproliferative activity assay |
|
|
|
TGI = 3.16 ��M |
27017549 |
OVCAR4 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
SK-MEL-2 |
Antiproliferative activity assay |
|
|
|
TGI = 3.16 ��M |
27017549 |
BT549 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
MOLT4 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
K562 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
HCC2998 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
HCC2998 |
Antiproliferative activity assay |
|
|
|
TGI = 3.16 ��M |
27017549 |
A549/ATCC |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
DU145 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
SR |
Antiproliferative activity assay |
|
|
|
GI50 = 3.16 ��M |
27017549 |
MCF7 |
Cytotoxicity assay |
|
|
|
IC50 = 3.18 ��M |
28927801 |
PC3 |
Cytotoxicity assay |
|
|
|
IC50 = 3.18 ��M |
28927801 |
MCF7 |
Cytotoxicity assay |
|
|
|
IC50 = 3.18 ��M |
27777009 |
A549 |
Antiproliferative activity assay |
|
|
|
IC50 = 3.19 ��M |
25778995 |
PC3 |
Cytotoxicity assay |
|
|
|
IC50 = 3.24 ��M |
27777009 |
HeLa |
Function assay |
|
|
|
IC50 = 3.3 ��M |
15225706 |
HeLa |
Function assay |
|
|
|
IC50 = 3.3 ��M |
15225706 |
LoVo |
Cytotoxicity assay |
|
|
|
IC50 = 3.3 ��M |
23454017 |
A375 |
Antiproliferative activity assay |
|
|
|
IC50 = 3.36 ��M |
29602674 |
HT-29 |
Antiproliferative activity assay |
|
|
|
IC50 = 3.37 ��M |
26991938 |
FLT3 gene-deficient U937 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.4 ��M |
21708468 |
FLT3 negative U937 |
Cytotoxicity assay |
|
|
|
GI50 = 3.4 ��M |
23618709 |
U937 |
Cytotoxicity assay |
|
|
|
GI50 = 3.4 ��M |
26081023 |
A375P |
Antiproliferative activity assay |
|
|
|
GI50 = 3.4 ��M |
29459144 |
ACHN |
Cytotoxicity assay |
|
|
|
IC50 = 3.4 ��M |
29517908 |
ACHN |
Cytotoxicity assay |
|
|
|
IC50 = 3.4 ��M |
29297688 |
HepG2 |
Function assay |
|
|
|
IC50 = 3.4 ��M |
26071861 |
A375P |
Cytotoxicity assay |
|
|
|
GI50 = 3.4 ��M |
24878193 |
HepG2 |
Cytotoxicity assay |
|
|
|
IC50 = 3.44 ��M |
28927801 |
HepG2 |
Cytotoxicity assay |
|
|
|
IC50 = 3.44 ��M |
27777009 |
ACHN |
Cytotoxicity assay |
|
|
|
IC50 = 3.5 ��M |
29786436 |
HepG2 |
Antiproliferative activity assay |
|
|
|
IC50 = 3.5 ��M |
25462265 |
HT-29 |
Cytotoxicity assay |
|
|
|
IC50 = 3.61 ��M |
24826815 |
HT-29 |
Antiproliferative activity assay |
|
|
|
IC50 = 3.61 ��M |
30216849 |
HT-29 |
Cytotoxicity assay |
|
|
|
IC50 = 3.61 ��M |
25086238 |
HT-29 |
Cytotoxicity assay |
|
|
|
IC50 = 3.61 ��M |
25440879 |
MCF7 |
Anticancer activity assay |
|
|
|
IC50 = 3.64 ��M |
29549841 |
Sf9 |
Function assay |
|
|
|
IC50 = 3.8 ��M |
21708468 |
Sf9 |
Function assay |
|
|
|
IC50 = 3.8 ��M |
23618709 |
Sf9 |
Function assay |
|
|
|
IC50 = 3.8 ��M |
26081023 |
A2058 |
Cytotoxicity assay |
|
|
|
IC50 = 3.8 ��M |
22708987 |
NCI-H460 |
Cytotoxicity assay |
|
|
|
IC50 = 3.9 ��M |
23454017 |
SK-MEL-30 |
Cytotoxicity assay |
|
|
|
IC50 = 3.9 ��M |
29461827 |
HT-29 |
Anticancer activity assay |
|
|
|
IC50 = 3.97 ��M |
29549841 |
SF268 |
Growth inhibition assay |
|
|
|
TGI = 3.98 ��M |
28088086 |
SNB75 |
Growth inhibition assay |
|
|
|
TGI = 3.98 ��M |
28088086 |
OVCAR3 |
Growth inhibition assay |
|
|
|
TGI = 3.98 ��M |
28088086 |
SNB19 |
Growth inhibition assay |
|
|
|
TGI = 3.98 ��M |
28088086 |
Hs 578T |
Growth inhibition assay |
|
|
|
TGI = 3.98 ��M |
28088086 |
TK10 |
Growth inhibition assay |
|
|
|
GI50 = 3.98 ��M |
28088086 |
BT549 |
Growth inhibition assay |
|
|
|
TGI = 3.98 ��M |
28088086 |
Caki1 |
Antiproliferative activity assay |
|
|
|
TGI = 3.98 ��M |
27017549 |
TK10 |
Antiproliferative activity assay |
|
|
|
GI50 = 3.98 ��M |
27017549 |
MDA-MB-435 |
Antiproliferative activity assay |
|
|
|
TGI = 3.98 ��M |
27017549 |
HCT116 |
Antiproliferative activity assay |
|
|
|
TGI = 3.98 ��M |
27017549 |
MDA-MB-231 |
Antiproliferative activity assay |
|
|
|
TGI = 3.98 ��M |
27017549 |
HepG2 |
Cytotoxicity assay |
|
|
|
IC50 = 4 ��M |
23454017 |
HT-29 |
Cytotoxicity assay |
|
|
|
IC50 = 4 ��M |
23454017 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 4 ��M |
23454017 |
HuH7 |
Cytotoxicity assay |
|
|
|
GI50 = 4 ��M |
23726028 |
PC3 |
Antiproliferative activity assay |
|
|
|
IC50 = 4.13 ��M |
25778995 |
HeLa |
Cytotoxicity assay |
|
|
|
IC50 = 4.163 ��M |
23362959 |
MDA-MB-436 |
Antiproliferative activity assay |
|
|
|
IC50 = 4.2 ��M |
29202403 |
MCF7 |
Cytotoxicity assay |
|
|
|
IC50 = 4.21 ��M |
27043268 |
MCF7 |
Cytotoxicity assay |
|
|
|
IC50 = 4.21 ��M |
28340913 |
LOXIMVI |
Antiproliferative activity assay |
|
|
|
IC50 = 4.25 ��M |
25778995 |
OVCAR4 |
Cytotoxicity assay |
|
|
|
TGI = 4.31 ��M |
26590508 |
WM1361 |
Antiproliferative activity assay |
|
|
|
GI50 = 4.345 ��M |
20148563 |
WM266.4 |
Growth inhibition assay |
|
|
|
GI50 = 4.5 ��M |
20199087 |
HepG2 |
Cytotoxicity assay |
|
|
|
GI50 = 4.5 ��M |
23726028 |
A549 |
Antiproliferative activity assay |
|
|
|
IC50 = 4.5 ��M |
23260578 |
LS174T |
Function assay |
|
|
|
IC50 = 4.52 ��M |
29266937 |
8505C |
Antiproliferative activity assay |
|
|
|
IC50 = 4.7 ��M |
29032031 |
OVCAR8 |
Cytotoxicity assay |
|
|
|
TGI = 4.73 ��M |
26590508 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
|
IC50 = 4.77 ��M |
20435479 |
B16-F1 |
Antiproliferative activity assay |
|
|
|
IC50 = 4.9 ��M |
18477505 |
WM164 |
Antiproliferative activity assay |
|
|
|
IC50 = 4.9 ��M |
17561392 |
B16-F1 |
Antiproliferative activity assay |
|
|
|
IC50 = 4.9 ��M |
20056548 |
MDA-MB-468 |
Cytotoxicity assay |
|
|
|
IC50 = 4.9 ��M |
26159483 |
786-O |
Cytotoxicity assay |
|
|
|
IC50 = 4.9 ��M |
29517908 |
786-O |
Cytotoxicity assay |
|
|
|
IC50 = 4.9 ��M |
29297688 |
WM266.4 |
Antiproliferative activity assay |
|
|
|
GI50 = 4.933 ��M |
20148563 |
WM266.4 |
Growth inhibition assay |
|
|
|
IC50 = 5 ��M |
19323560 |
WM164 |
Antiproliferative activity assay |
|
|
|
IC50 = 5 ��M |
20056548 |
HepG2 |
Antiproliferative activity assay |
|
|
|
IC50 = 5 ��M |
23260578 |
HepG2 |
Antiproliferative activity assay |
|
|
|
IC50 = 5 ��M |
23932071 |
NCI-H23 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
NCI-H322M |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
NCI-H460 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
NCI-H522 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
HT-29 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
CCRF-CEM |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
SW620 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
HOP92 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
786-0 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
MDA-MB-435 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
PC3 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
UACC257 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
SKOV3 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
RXF393 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
T47D |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
MDA-MB-468 |
Growth inhibition assay |
|
|
|
TGI = 5.01 ��M |
28088086 |
UACC62 |
Antiproliferative activity assay |
|
|
|
TGI = 5.01 ��M |
27017549 |
UACC257 |
Antiproliferative activity assay |
|
|
|
TGI = 5.01 ��M |
27017549 |
SK-MEL-5 |
Antiproliferative activity assay |
|
|
|
LC50 = 5.01 ��M |
27017549 |
M14 |
Antiproliferative activity assay |
|
|
|
TGI = 5.01 ��M |
27017549 |
NCI-H23 |
Antiproliferative activity assay |
|
|
|
TGI = 5.01 ��M |
27017549 |
SF295 |
Antiproliferative activity assay |
|
|
|
TGI = 5.01 ��M |
27017549 |
HOP92 |
Antiproliferative activity assay |
|
|
|
TGI = 5.01 ��M |
27017549 |
BT549 |
Antiproliferative activity assay |
|
|
|
TGI = 5.01 ��M |
27017549 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
|
IC50 = 5.1 ��M |
26159483 |
DU145 |
Cytotoxicity assay |
|
|
|
IC50 = 5.1 ��M |
22708987 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 5.21 ��M |
20181414 |
HeLa |
Cytotoxicity assay |
|
|
|
IC50 = 5.23 ��M |
26342867 |
786-O |
Cytotoxicity assay |
|
|
|
IC50 = 5.3 ��M |
29786436 |
HCT116 |
Antiproliferative activity assay |
|
|
|
GI50 = 5.4 ��M |
15225706 |
A375 |
Antiproliferative activity assay |
|
|
|
IC50 = 5.4 ��M |
18477505 |
SK-MEL-188 |
Antiproliferative activity assay |
|
|
|
IC50 = 5.4 ��M |
17561392 |
A375 |
Antiproliferative activity assay |
|
|
|
IC50 = 5.4 ��M |
20056548 |
MCF7 |
Cytotoxicity assay |
|
|
|
IC50 = 5.5 ��M |
26159483 |
A375 |
Antiproliferative activity assay |
|
|
|
IC50 = 5.58 ��M |
19464887 |
A375P |
Cytotoxicity assay |
|
|
|
IC50 = 5.58 ��M |
20797858 |
A375P |
Antiproliferative activity assay |
|
|
|
GI50 = 5.58 ��M |
21353571 |
A375P |
Growth inhibition assay |
|
|
|
GI50 = 5.58 ��M |
22014755 |
A375P |
Growth inhibition assay |
|
|
|
GI50 = 5.58 ��M |
20149658 |
A375P |
Antiproliferative activity assay |
|
|
|
GI50 = 5.58 ��M |
20466542 |
A375P |
Antiproliferative activity assay |
|
|
|
IC50 = 5.6 ��M |
19857963 |
A375P |
Antiproliferative activity assay |
|
|
|
IC50 = 5.6 ��M |
21592628 |
A375P |
Antiproliferative activity assay |
|
|
|
IC50 = 5.6 ��M |
22033063 |
A375P |
Cytotoxicity assay |
|
|
|
IC50 = 5.6 ��M |
19897366 |
A375P |
Antiproliferative activity assay |
|
|
|
IC50 = 5.6 ��M |
22647720 |
HCT116 |
Cytotoxicity assay |
|
|
|
IC50 = 5.65 ��M |
24215818 |
SH-SY5Y |
Antiproliferative activity assay |
|
|
|
IC50 = 5.73 ��M |
24315192 |
HepG2 |
Cytotoxicity assay |
|
|
|
IC50 = 5.74 ��M |
25461318 |
Bel7402 |
Cytotoxicity assay |
|
|
|
IC50 = 5.8 ��M |
23454017 |
HT-29 |
Cytotoxicity assay |
|
|
|
IC50 = 5.9 ��M |
28865276 |
melanoma |
Growth inhibition assay |
|
|
|
IC50 = 6.1 ��M |
16392826 |
K562 |
Antiproliferative activity assay |
|
|
|
GI50 = 6.2 ��M |
21708468 |
HepG2 |
Cytotoxicity assay |
|
|
|
IC50 = 6.2 ��M |
28865276 |
A549 |
Anticancer activity assay |
|
|
|
IC50 = 6.21 ��M |
29549841 |
SMMC7721 |
Antiproliferative activity assay |
|
|
|
IC50 = 6.23 ��M |
22721924 |
HepG2 |
Antiproliferative activity assay |
|
|
|
IC50 = 6.3 ��M |
23932071 |
SF295 |
Growth inhibition assay |
|
|
|
TGI = 6.31 ��M |
28088086 |
SK-MEL-2 |
Growth inhibition assay |
|
|
|
TGI = 6.31 ��M |
28088086 |
OVCAR5 |
Growth inhibition assay |
|
|
|
TGI = 6.31 ��M |
28088086 |
UO31 |
Growth inhibition assay |
|
|
|
TGI = 6.31 ��M |
28088086 |
A498 |
Antiproliferative activity assay |
|
|
|
TGI = 6.31 ��M |
27017549 |
MALME-3M |
Antiproliferative activity assay |
|
|
|
TGI = 6.31 ��M |
27017549 |
U251 |
Antiproliferative activity assay |
|
|
|
TGI = 6.31 ��M |
27017549 |
SK-MEL-2 |
Antiproliferative activity assay |
|
|
|
LC50 = 6.31 ��M |
27017549 |
RPMI8226 |
Antiproliferative activity assay |
|
|
|
TGI = 6.31 ��M |
27017549 |
HCC2998 |
Antiproliferative activity assay |
|
|
|
LC50 = 6.31 ��M |
27017549 |
NCI-H522 |
Antiproliferative activity assay |
|
|
|
TGI = 6.31 ��M |
27017549 |
HUVEC |
Antiproliferative activity assay |
|
|
|
IC50 = 6.42 ��M |
23644219 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 6.53 ��M |
27043268 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 6.53 ��M |
28340913 |
LoVo |
Antiproliferative activity assay |
|
|
|
IC50 = 6.56 ��M |
24315192 |
A375 |
Function assay |
|
|
|
IC50 = 6.599 ��M |
21807507 |
HCT116 |
Function assay |
|
|
|
GI50 = 6.6 ��M |
15225706 |
HepG2 |
Cytotoxicity assay |
|
|
|
IC50 = 6.7 ��M |
26159483 |
BCPAP |
Antiproliferative activity assay |
|
|
|
IC50 = 6.7 ��M |
29032031 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 6.7 ��M |
28865276 |
PC3 |
Cytotoxicity assay |
|
|
|
IC50 = 6.8 ��M |
23021967 |
SGC7901 |
Cytotoxicity assay |
|
|
|
IC50 = 6.9 ��M |
23454017 |
OS-RC2 |
Cytotoxicity assay |
|
|
|
IC50 = 7 ��M |
29517908 |
OS-RC2 |
Cytotoxicity assay |
|
|
|
IC50 = 7 ��M |
29297688 |
COLO205 |
Antiproliferative activity human |
|
|
|
IC50 = 7.04 ��M |
28242553 |
rhabdomyosarcoma |
Cytotoxicity activity against human |
|
|
|
CC50 = 7.05 ��M |
27288186 |
HuH7 |
Cytotoxicity assay |
|
|
|
IC50 = 7.1 ��M |
26159483 |
MDA-MB-231 |
Antiproliferative activity assay |
|
|
|
IC50 = 7.18 ��M |
22721924 |
FLT3-negative K562 |
Cytotoxicity assay |
|
|
|
GI50 = 7.3 ��M |
23618709 |
K562 |
Function assay |
|
|
|
GI50 = 7.3 ��M |
26081023 |
K562 |
Function assay |
|
|
|
GI50 = 7.3 ��M |
26081023 |
MCF7 |
Antiproliferative activity assay |
|
|
|
IC50 = 7.33 ��M |
23644219 |
A549 |
Cytotoxicity assay |
|
|
|
TGI = 7.36 ��M |
26590508 |
WI38 |
Cytotoxicity assay |
|
|
|
IC50 = 7.54 ��M |
24826815 |
A375 |
Cytotoxicity assay |
|
|
|
IC50 = 7.56 ��M |
24215818 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
|
IC50 = 7.62 ��M |
20181414 |
786-0 |
Cytotoxicity assay |
|
|
|
TGI = 7.62 ��M |
26590508 |
HS27 |
Antiproliferative activity assay |
|
|
|
IC50 = 7.8 ��M |
19857963 |
HS27 |
Cytotoxicity assay |
|
|
|
IC50 = 7.8 ��M |
19897366 |
HCT116 |
Cytotoxicity assay |
|
|
|
IC50 = 7.8 ��M |
22483592 |
HS27 |
Antiproliferative activity assay |
|
|
|
IC50 = 7.85 ��M |
19464887 |
HS27 |
Antiproliferative activity assay |
|
|
|
GI50 = 7.85 ��M |
21353571 |
A549/ATCC |
Growth inhibition assay |
|
|
|
TGI = 7.94 ��M |
28088086 |
DU145 |
Growth inhibition assay |
|
|
|
TGI = 7.94 ��M |
28088086 |
NCI/ADR-RES |
Growth inhibition assay |
|
|
|
TGI = 7.94 ��M |
28088086 |
MCF7 |
Growth inhibition assay |
|
|
|
TGI = 7.94 ��M |
28088086 |
PC3 |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
UO31 |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
NCI-ADR-RES |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
LOXIMVI |
Antiproliferative activity assay |
|
|
|
LC50 = 7.94 ��M |
27017549 |
SK-MEL-28 |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
KM12 |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
COLO205 |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
HT-29 |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
NCI-H226 |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
HOP62 |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
T47D |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
MDA-MB-468 |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
EKVX |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
MCF7 |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
Hs 578T |
Antiproliferative activity assay |
|
|
|
TGI = 7.94 ��M |
27017549 |
MGC803 |
Antiproliferative activity assay |
|
|
|
IC50 = 7.99 ��M |
26560049 |
HCT116 |
Antiproliferative activity assay |
|
|
|
IC50 = 8.08 ��M |
24440479 |
PC3 |
Cytotoxicity assay |
|
|
|
IC50 = 8.08 ��M |
27043268 |
HCT116 |
Antiproliferative activity assay |
|
|
|
IC50 = 8.08 ��M |
23644219 |
WM266.4 |
Antiproliferative activity assay |
|
|
|
GI50 = 8.1 ��M |
23025996 |
WM266.4 |
Antiproliferative activity assay |
|
|
|
GI50 = 8.12 ��M |
22583669 |
Ketr3 |
Antiproliferative activity assay |
|
|
|
IC50 = 8.27 ��M |
30216849 |
A375 |
Antiproliferative activity assay |
|
|
|
IC50 = 8.27 ��M |
30216849 |
HepG2 |
Antiproliferative activity assay |
|
|
|
IC50 = 8.27 ��M |
30216849 |
MX1 |
Antiproliferative activity assay |
|
|
|
IC50 = 8.27 ��M |
30216849 |
MX1 |
Cytotoxicity assay |
|
|
|
IC50 = 8.27 ��M |
24675135 |
WM266.4 |
Growth inhibition assay |
|
|
|
GI50 = 8.3 ��M |
22361686 |
PLC/PRF/5 |
Cytotoxicity assay |
|
|
|
IC50 = 8.3 ��M |
21531053 |
A375 |
Antiproliferative activity assay |
|
|
|
IC50 = 8.33 ��M |
29886324 |
HCT116 |
Cytotoxicity assay |
|
|
|
IC50 = 8.41 ��M |
29631788 |
WI38 |
Cytotoxicity assay |
|
|
|
IC50 = 8.42 ��M |
26991938 |
HepG2 |
Cytotoxicity assay |
|
|
|
IC50 = 8.42 ��M |
27162123 |
HepG2 |
Cytotoxicity assay |
|
|
|
IC50 = 8.42 ��M |
23871909 |
HT-29 |
Antiproliferative activity assay |
|
|
|
IC50 = 8.44 ��M |
29602674 |
HepG2 |
Cytotoxicity assay |
|
|
|
IC50 = 8.67 ��M |
24675135 |
MCF7 |
Cytotoxicity assay |
|
|
|
IC50 = 8.83 ��M |
20435479 |
MCF7 |
Cytotoxicity assay |
|
|
|
IC50 = 9.12 ��M |
24300920 |
HepG2 |
Antiproliferative activity assay |
|
|
|
IC50 = 9.14 ��M |
26560049 |
A375 |
Cytotoxicity assay |
|
|
|
IC50 = 9.17 ��M |
24675135 |
MGC803 |
Antiproliferative activity assay |
|
|
|
IC50 = 9.2 ��M |
29032031 |
SKOV3 |
Cytotoxicity assay |
|
|
|
IC50 = 9.25 ��M |
24300920 |
RS4:11 |
Function assay |
|
|
|
GI50 = 9.3 ��M |
26081023 |
RS4:11 |
Cytotoxicity assay |
|
|
|
GI50 = 9.3 ��M |
23618709 |
MIAPaCa2 |
Antiproliferative activity assay |
|
|
|
IC50 = 9.32 ��M |
29032031 |
PANC1 |
Growth inhibition assay |
|
|
|
IC50 = 9.32 ��M |
29102175 |
MHCC97H |
Growth inhibition assay |
|
|
|
IC50 = 9.32 ��M |
29102175 |
RS4:11 |
Antiproliferative activity assay |
|
|
|
GI50 = 9.4 ��M |
21708468 |
Hep3B |
Cytotoxicity assay |
|
|
|
IC50 = 9.4 ��M |
28865276 |
LoVo |
Growth inhibition assay |
|
|
|
IC50 = 9.47 ��M |
29102175 |
SMMC7721 |
Antiproliferative activity assay |
|
|
|
IC50 = 9.96 ��M |
25637123 |
MCF7 |
Cytotoxicity assay |
|
|
|
TGI = 9.97 ��M |
26590508 |
IGROV1 |
Growth inhibition assay |
|
|
|
TGI = 10 ��M |
28088086 |
ACHN |
Growth inhibition assay |
|
|
|
TGI = 10 ��M |
28088086 |
TK10 |
Growth inhibition assay |
|
|
|
TGI = 10 ��M |
28088086 |
786-0 |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
SN12C |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
Caki1 |
Antiproliferative activity assay |
|
|
|
LC50 = 10 ��M |
27017549 |
TK10 |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
RXF393 |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
OVCAR8 |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
SNB75 |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
NCI-H322M |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
MDA-MB-435 |
Antiproliferative activity assay |
|
|
|
LC50 = 10 ��M |
27017549 |
SF539 |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
SF268 |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
NCI-H460 |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
DU145 |
Antiproliferative activity assay |
|
|
|
TGI = 10 ��M |
27017549 |
K1 |
Antiproliferative activity assay |
|
|
|
IC50 = 10.2 ��M |
29032031 |
Bel7402 |
Cytotoxicity assay |
|
|
|
IC50 = 10.26 ��M |
21504204 |
Bel7402 |
Growth inhibition assay |
|
|
|
IC50 = 10.31 ��M |
29102175 |
OVCAR3 |
Cytotoxicity assay |
|
|
|
TGI = 10.32 ��M |
26590508 |
SGC7901 |
Cytotoxicity assay |
|
|
|
IC50 = 10.37 ��M |
20435479 |
SNB75 |
Cytotoxicity assay |
|
|
|
TGI = 10.42 ��M |
26590508 |
A431 |
Antiproliferative activity assay |
|
|
|
IC50 = 10.46 ��M |
29032031 |
SMMC7721 |
Antiproliferative activity assay |
|
|
|
IC50 = 10.61 ��M |
29032031 |
GES-1 |
Cytotoxicity assay |
|
|
|
IC50 = 10.68 ��M |
27162123 |
H460 |
Cytotoxicity assay |
|
|
|
IC50 = 10.8 ��M |
24300920 |
BGC823 |
Antiproliferative activity assay |
|
|
|
IC50 = 10.91 ��M |
22721924 |
Hep3B |
Cytotoxicity assay |
|
|
|
IC50 = 11.2 ��M |
28342400 |
MCF7 |
Cytotoxicity assay |
|
|
|
IC50 = 11.34 ��M |
27162123 |
MCF7 |
Cytotoxicity assay |
|
|
|
IC50 = 11.34 ��M |
23871909 |
SK-MEL-2 |
Antiproliferative activity human |
|
|
|
IC50 = 11.35 ��M |
28242553 |
HepG2 |
Cytotoxicity assay |
|
|
|
IC50 = 11.49 ��M |
21504204 |
A375P |
Antiproliferative activity assay |
|
|
|
IC50 = 11.5 ��M |
22014559 |
SGC7901 |
Cytotoxicity assay |
|
|
|
IC50 = 11.5 ��M |
24300920 |
HeLa |
Antiproliferative activity assay |
|
|
|
IC50 = 12.01 ��M |
29103873 |
PANC1 |
Cytotoxicity assay |
|
|
|
IC50 = 12.3 ��M |
24300920 |
HepG2 |
Antiproliferative activity assay |
|
|
|
IC50 = 12.54 ��M |
29032031 |
A549 |
Antiproliferative activity assay |
|
|
|
IC50 = 12.54 ��M |
23644219 |
Caki1 |
Growth inhibition assay |
|
|
|
TGI = 12.59 ��M |
28088086 |
OVCAR8 |
Growth inhibition assay |
|
|
|
TGI = 12.59 ��M |
28088086 |
SKOV3 |
Antiproliferative activity assay |
|
|
|
TGI = 12.6 ��M |
27017549 |
ACHN |
Antiproliferative activity assay |
|
|
|
TGI = 12.6 ��M |
27017549 |
OVCAR3 |
Antiproliferative activity assay |
|
|
|
TGI = 12.6 ��M |
27017549 |
OVCAR4 |
Antiproliferative activity assay |
|
|
|
TGI = 12.6 ��M |
27017549 |
HCT15 |
Antiproliferative activity assay |
|
|
|
TGI = 12.6 ��M |
27017549 |
SW620 |
Antiproliferative activity assay |
|
|
|
TGI = 12.6 ��M |
27017549 |
A549/ATCC |
Antiproliferative activity assay |
|
|
|
TGI = 12.6 ��M |
27017549 |
MDA-MB-468 |
Cytotoxicity assay |
|
|
|
TGI = 13.09 ��M |
26590508 |
SK-MEL-28 |
Cytotoxicity assay |
|
|
|
TGI = 13.39 ��M |
26590508 |
A549 |
Antiproliferative activity assay |
|
|
|
IC50 = 13.64 ��M |
26560049 |
A375 |
Antiproliferative activity human |
|
|
|
IC50 = 13.64 ��M |
28242553 |
A375 |
Antiproliferative activity assay |
|
|
|
IC50 = 13.64 ��M |
25462267 |
K562 |
Antiproliferative activity assay |
|
|
|
IC50 = 13.85 ��M |
23644219 |
Hep3B |
Cytotoxicity assay |
|
|
|
IC50 = 14.08 ��M |
21504204 |
T47D |
Cytotoxicity assay |
|
|
|
TGI = 14.38 ��M |
26590508 |
NCI-H226 |
Cytotoxicity assay |
|
|
|
TGI = 14.42 ��M |
26590508 |
MDA-MB-231 |
Antiproliferative activity assay |
|
|
|
IC50 = 14.62 ��M |
24440479 |
MDA-MB-231 |
Antiproliferative activity assay |
|
|
|
IC50 = 14.62 ��M |
23644219 |
NCI-H522 |
Cytotoxicity assay |
|
|
|
TGI = 14.82 ��M |
26590508 |
SK-MEL-2 |
Cytotoxicity assay |
|
|
|
TGI = 14.85 ��M |
26590508 |
OS-RC2 |
Cytotoxicity assay |
|
|
|
IC50 = 15 ��M |
29786436 |
HepG2 |
Antiproliferative activity assay |
|
|
|
IC50 = 15 ��M |
29103873 |
fibroblast |
Antiproliferative activity assay |
|
|
|
IC50 = 15.1 ��M |
18477505 |
HT-29 |
Cytotoxicity assay |
|
|
|
IC50 = 15.2 ��M |
24675135 |
U87MG |
Cytotoxicity assay |
|
|
|
IC50 = 15.57 ��M |
24826815 |
BT549 |
Antiproliferative activity assay |
|
|
|
LC50 = 15.8 ��M |
27017549 |
GES-1 |
Cytotoxicity assay |
|
|
|
IC50 = 15.8 ��M |
23871909 |
SNB19 |
Antiproliferative activity assay |
|
|
|
TGI = 15.85 ��M |
27017549 |
IGROV1 |
Antiproliferative activity assay |
|
|
|
TGI = 15.9 ��M |
27017549 |
HCT116 |
Antiproliferative activity assay |
|
|
|
LC50 = 15.9 ��M |
27017549 |
OS-RC2 |
Cytotoxicity assay |
|
|
|
IC50 = 16 ��M |
23454017 |
A375 |
Cytotoxicity assay |
|
|
|
IC50 = 16.24 ��M |
25461318 |
SKOV3 |
Cytotoxicity assay |
|
|
|
TGI = 16.36 ��M |
26590508 |
WM1361 |
Antiproliferative activity assay |
|
|
|
IC50 = 16.44 ��M |
29602674 |
MKN28 |
Antiproliferative activity assay |
|
|
|
IC50 = 17 ��M |
29032031 |
SMMC7721 |
Cytotoxicity assay |
|
|
|
IC50 = 17.3 ��M |
21504204 |
UACC257 |
Cytotoxicity assay |
|
|
|
TGI = 17.33 ��M |
26590508 |
EAhy926 |
Antiangiogenic activity assay |
|
|
|
IC50 = 18.52 ��M |
29032031 |
SMMC7721 |
Cytotoxicity assay |
|
|
|
IC50 = 18.7 ��M |
24300920 |
Ketr3 |
Cytotoxicity assay |
|
|
|
IC50 = 18.8 ��M |
24675135 |
NCI-H522 |
Cytotoxicity assay |
|
|
|
IC50 = 19.26 ��M |
25461318 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 19.54 ��M |
27162123 |
SH-SY5Y |
Cytotoxicity assay |
|
|
|
IC50 = 19.54 ��M |
23871909 |
MGC803 |
Antiproliferative activity assay |
|
|
|
IC50 = 19.92 ��M |
29103873 |
EKVX |
Growth inhibition assay |
|
|
|
TGI = 19.95 ��M |
28088086 |
OVCAR5 |
Antiproliferative activity assay |
|
|
|
TGI = 20 ��M |
27017549 |
UACC62 |
Antiproliferative activity assay |
|
|
|
LC50 = 20 ��M |
27017549 |
UACC257 |
Antiproliferative activity assay |
|
|
|
LC50 = 20 ��M |
27017549 |
MDA-MB-231 |
Antiproliferative activity assay |
|
|
|
LC50 = 20 ��M |
27017549 |
U87 |
Cytotoxicity assay |
|
|
|
IC50 = 21.07 ��M |
20435479 |
EJ |
Cytotoxicity assay |
|
|
|
IC50 = 22.9 ��M |
24300920 |
HCT116 |
Antiproliferative activity assay |
|
|
|
IC50 = 23.31 ��M |
29602674 |
HOP62 |
Cytotoxicity assay |
|
|
|
TGI = 23.55 ��M |
26590508 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
|
TGI = 23.93 ��M |
26590508 |
PC3 |
Antiproliferative activity assay |
|
|
|
IC50 = 24.2 ��M |
24440479 |
PC3 |
Antiproliferative activity assay |
|
|
|
IC50 = 24.2 ��M |
23644219 |
EAhy926 |
Antiproliferative activity assay |
|
|
|
IC50 = 24.36 ��M |
28068599 |
EAhy926 |
Anti-angiogenic activity in human |
|
|
|
IC50 = 24.36 ��M |
29102175 |
U251 |
Cytotoxicity assay |
|
|
|
IC50 = 24.71 ��M |
20435479 |
NIH/3T3 |
Antiproliferative activity assay |
|
|
|
IC50 = 24.75 ��M |
21592628 |
NIH/3T3 |
Antiproliferative activity assay |
|
|
|
IC50 = 24.75 ��M |
22647720 |
DU145 |
Cytotoxicity assay |
|
|
|
IC50 = 24.91 ��M |
27162123 |
DU145 |
Cytotoxicity assay |
|
|
|
IC50 = 24.91 ��M |
23871909 |
U251 |
Antiproliferative activity assay |
|
|
|
LC50 = 25.1 ��M |
27017549 |
M14 |
Antiproliferative activity assay |
|
|
|
LC50 = 25.1 ��M |
27017549 |
NCI-H522 |
Antiproliferative activity assay |
|
|
|
LC50 = 25.1 ��M |
27017549 |
OVCAR4 |
Growth inhibition assay |
|
|
|
TGI = 25.12 ��M |
28088086 |
SH-SY5Y |
Cytotoxicity assay |
|
|
|
IC50 = 27.71 ��M |
27162123 |
A549 |
Cytotoxicity assay |
|
|
|
IC50 = 27.71 ��M |
23871909 |
PLC/PRF/5 |
Cytotoxicity assay |
|
|
|
IC50 = 29.9 ��M |
28109948 |
SK-MEL-5 |
Cytotoxicity assay |
|
|
|
TGI = 31.26 ��M |
26590508 |
A498 |
Antiproliferative activity assay |
|
|
|
LC50 = 31.6 ��M |
27017549 |
SK-MEL-28 |
Antiproliferative activity assay |
|
|
|
LC50 = 31.6 ��M |
27017549 |
KM12 |
Antiproliferative activity assay |
|
|
|
LC50 = 31.6 ��M |
27017549 |
COLO205 |
Antiproliferative activity assay |
|
|
|
LC50 = 31.6 ��M |
27017549 |
NCI-H226 |
Antiproliferative activity assay |
|
|
|
LC50 = 31.6 ��M |
27017549 |
SF295 |
Antiproliferative activity assay |
|
|
|
LC50 = 31.6 ��M |
27017549 |
HOP62 |
Antiproliferative activity assay |
|
|
|
LC50 = 31.6 ��M |
27017549 |
T47D |
Antiproliferative activity assay |
|
|
|
LC50 = 31.6 ��M |
27017549 |
MHCC97L |
Cytotoxicity assay |
|
|
|
IC50 = 34.41 ��M |
28109948 |
MDA-MB-231 |
Antiproliferative activity assay |
|
|
|
IC50 = 35 ��M |
24315192 |
MDA-MB-231 |
Cytotoxicity assay |
|
|
|
IC50 = 36 ��M |
22483592 |
B16-BL6 |
Cytotoxicity assay |
|
|
|
IC50 = 36.48 ��M |
29631788 |
UO31 |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
SN12C |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
RXF393 |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
SNB75 |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
SF268 |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
NCI-H23 |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
HT-29 |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
HOP92 |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
NCI-H460 |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
SW620 |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
MDA-MB-468 |
Antiproliferative activity assay |
|
|
|
LC50 = 39.8 ��M |
27017549 |
MALME-3M |
Growth inhibition assay |
|
|
|
TGI = 39.81 ��M |
28088086 |