Home Neuronal Signaling AChR antagonist Scopolamine HBr trihydrate For research use only.

Scopolamine HBr trihydrate

Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.

Scopolamine HBr trihydrate Chemical Structure

Scopolamine HBr trihydrate Chemical Structure

CAS No. 6533-68-2

Purity & Quality Control

Scopolamine HBr trihydrate Related Products

Signaling Pathway

AChR Signaling Pathways

AChR Signaling Pathway

Biological Activity

Description Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.
Targets
mAChR [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05759481 Recruiting
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Milton S. Hershey Medical Center
 February 1 2024 Phase 2
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Battelle Memorial Institute
 June 2 2020 Phase 1
NCT03874130 Unknown status
Major Depressive Disorder (MDD)
Repurposed Therapeutics Inc.
 August 1 2018 Phase 1
NCT03294109 Completed
Pain Postoperative|Analgesics Opioid|Analgesics Non-Narcotic|Physiological Effects of Drugs|Peripheral Nervous System Agents|Patient Satisfaction|Return to Work|Activity Sexual
University of California Los Angeles
 January 1 2018 Phase 4

Chemical Information & Solubility

Molecular Weight 438.31 Formula

C17H28BrNO7
CAS No. 6533-68-2 SDF --
Smiles CN1C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4.O.O.O.Br
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 88 mg/mL ( (200.77 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 88 mg/mL

Ethanol : 15 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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