Home Neuronal Signaling AChR activator Pralidoxime chloride For research use only.

Pralidoxime chloride

Synonyms: 2-PAM (chloride)

Pralidoxime chloride (2-PAM) is an antidote to organophosphate pesticides and chemicals; An acetylcholinesterase (AChE) reactivator.

Pralidoxime chloride Chemical Structure

Pralidoxime chloride Chemical Structure

CAS No. 51-15-0

Purity & Quality Control

Batch: S457501 Water]34 mg/mL]false]Ethanol]1 mg/mL]false]DMSO]Insoluble]false Purity: 99.96%
99.96

Pralidoxime chloride Related Products

Signaling Pathway

AChR Signaling Pathways

AChR Signaling Pathway

Biological Activity

Description Pralidoxime chloride (2-PAM) is an antidote to organophosphate pesticides and chemicals; An acetylcholinesterase (AChE) reactivator.
In vitro
In vitro The application of pralidoxime allowed the regeneration of an important fraction of inhibited AChE, process which is concentration-dependent[1].

Chemical Information & Solubility

Molecular Weight 172.61 Formula

C7H9N2O.Cl
CAS No. 51-15-0 SDF Download Pralidoxime chloride SDF
Smiles C[N+]1=CC=CC=C1C=NO.[Cl-]
Storage (From the date of receipt)

In vitro
Batch:

Water : 34 mg/mL

Ethanol : 1 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Pralidoxime chloride | Pralidoxime chloride ic50 | Pralidoxime chloride price | Pralidoxime chloride cost | Pralidoxime chloride solubility dmso | Pralidoxime chloride purchase | Pralidoxime chloride manufacturer | Pralidoxime chloride research buy | Pralidoxime chloride order | Pralidoxime chloride mouse | Pralidoxime chloride chemical structure | Pralidoxime chloride mw | Pralidoxime chloride molecular weight | Pralidoxime chloride datasheet | Pralidoxime chloride supplier | Pralidoxime chloride in vitro | Pralidoxime chloride cell line | Pralidoxime chloride concentration | Pralidoxime chloride nmr