Home Endocrinology & Hormones Glucocorticoid Receptor agonist - Immunology & Inflammation related modulator - Apoptosis related inhibitor - Autophagy inhibitor - ACE activator - Interleukins inhibitor Methylprednisolone Acetate For research use only.

Methylprednisolone Acetate

Synonyms: NSC-19987 acetate, Medrol acetate

Methylprednisolone (NSC-19987, Medrol) acetate is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.

Methylprednisolone Acetate Chemical Structure

Methylprednisolone Acetate Chemical Structure

CAS No. 53-36-1

Purity & Quality Control

Batch: S597301 DMSO]86 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 99.55%
99.55

Methylprednisolone Acetate Related Products

Biological Activity

Description Methylprednisolone (NSC-19987, Medrol) acetate is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.
Targets
glucocorticoid receptor [1] ACE2 [1] IL-6 [1]

Chemical Information & Solubility

Molecular Weight 416.51 Formula

C24H32O6
CAS No. 53-36-1 SDF --
Smiles CC1CC2C3CCC(O)(C(=O)COC(C)=O)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 86 mg/mL ( (206.47 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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