Magrolimab (anti-CD47)

Synonyms: 5F9, GS-4721,Hu5F9 G4,ONO 7913

Catalog No.A2036 Purity:99%

Magrolimab (anti-CD47) (5F9, GS-4721,Hu5F9 G4,ONO 7913) is a first-in-class macrophage immune checkpoint inhibitor that mainly binds to N-terminal pyroglutamate of CD47.

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Purity & Quality Control

Batch: Purity: 99% Protein concentration: 7.31mg/ml Endotoxin Level: ＜1EU/mg

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description	Magrolimab (anti-CD47) (5F9, GS-4721,Hu5F9 G4,ONO 7913) is a first-in-class macrophage immune checkpoint inhibitor that mainly binds to N-terminal pyroglutamate of CD47.

References
[1] Bo Huang, et al. Comput Struct Biotechnol J . 2021 Oct 1;19:5494-5503.

References

[1] Bo Huang, et al. Comput Struct Biotechnol J . 2021 Oct 1;19:5494-5503.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	2169232-81-7
Molecular Weight	146 KD
Isotype	Human IgG4
Application	Magrolimab (anti-CD47)
Source	CHO cells
Sterility	0.2 μM filtered
Formulation	PBS Buffer, PH 7.4
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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