Home Metabolism THR activator Liothyronine Sodium For research use only.

Liothyronine Sodium

Synonyms: Cytomel

Liothyronine Sodium(Cytomel) is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.

Liothyronine Sodium Chemical Structure

Liothyronine Sodium Chemical Structure

CAS No. 55-06-1

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Liothyronine Sodium Related Products

Biological Activity

Description Liothyronine Sodium(Cytomel) is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.
Targets
thyroid hormone receptorα [1] thyroid hormone receptor β-1 [1]
In vitro
In vitro

Liothyronine Sodium is the most potent form of thyroid hormone. Chemically, it is nearly identical to triiodothyronine (T3). It targets thyroid hormone receptorα[1] and thyroid hormone receptor β-1 [2]. As such, it acts on the body to increase the basal metabolic rate, effect protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness.

Chemical Information & Solubility

Molecular Weight 672.96 Formula

C15H12I3NO4.Na
CAS No. 55-06-1 SDF Download Liothyronine Sodium SDF
Smiles C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)[O-])N)I)I)O.[Na+]
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( (148.59 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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