Home Biosimilar Antibodies Protein Tyrosine Kinase IGF-1R null Ganitumab (Anti-IGF-1R / CD221) For research use only.
Not for use in humans.

Ganitumab (Anti-IGF-1R / CD221)

Synonyms: AMG 479; Human Anti-IGF-1R Recombinant Antibody

Ganitumab (Anti-IGF-1R / CD221) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (KD=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. MW: 145.5 KD.

Ganitumab (Anti-IGF-1R / CD221)

Purity & Quality Control

Batch: Purity: 99% Protein concentration: 5.97mg/ml Endotoxin Level: ＜1EU/mg
99

Choose Selective IGF-1R Inhibitors

Name Citation IGF-1R Insulin Receptor Others
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NVP-ADW742 22
BMS-536924 24 FAK,MEK,LCK
AG-1024 26
GSK1838705A 18 ALK
BMS-754807 51 TrkB,Met,TrkA
PQ 401 3
Picropodophyllin (PPP) 41
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Ganitumab (Anti-IGF-1R / CD221) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (KD=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. MW: 145.5 KD.

Product Details

CAS No. 905703-97-1
Molecular Weight 145.5 kDa
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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