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Fremanezumab (Anti-CALCA / CGRP)

Synonyms: TEV-48125

Catalog No.A2791 Purity:≥99%

Fremanezumab (Anti-CALCA / CGRP) is a humanized IgG2a monoclonal antibody that selectively and potently targets calcitonin gene-related peptide (CGRP). Fremanezumab has the potential for chronic migraine research.. MW: 145.5 kD.

Fremanezumab (Anti-CALCA / CGRP)

Purity & Quality Control

≥99

Choose Selective CGRP Receptor Inhibitors

Name	Citation	CGRP
Ubrogepant	0	++
Olcegepant	0	+++

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description	Fremanezumab (Anti-CALCA / CGRP) is a humanized IgG2a monoclonal antibody that selectively and potently targets calcitonin gene-related peptide (CGRP). Fremanezumab has the potential for chronic migraine research.. MW: 145.5 kD.

References

[1] Silberstein SD, et al. N Engl J Med. 2017;377(22):2113-2122.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1655501-53-3
Molecular Weight	145.5
Isotype	Human IgG2SA
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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