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CGRP Receptor

Isoform-selective Products

CGRP Receptor Products

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  • CGRP Receptor Antibodies (2)
  • CGRP Receptor Antagonists (5)
  • New CGRP Receptor Products
Catalog No. Product Name Information Product Use Citations Product Validations
E1980New Atogepant Atogepant(MK-8031, AGN-241689) is a potent, selective, orally available antagonist of the calcitonin gene-related peptide (CGRP) receptor, with ki of 0.026 nM for human CGRP receptor. It is used for the preventive treatment episodic migraine.
E1824New Vazegepant hydrochloride Vazegepant hydrochloride (BHV-3500, Zavegepant), is a highly potent, selective, and structurally unique small molecule antagonist of CGRP receptor. It can also be used for the acute treatment of migraine.
S6659 Rimegepant (BMS-927711) Rimegepant (BMS-927711, BHV-3000) is a potent, selective, competitive human calcitonin gene-related peptide (CGRP) receptor antagonist with ki of 0.027 nM.
E1280 Ubrogepant Ubrogepant (MK-1602) is an antagonist of human calcitonin gene-related peptide receptor (CGRP). It potently blocks human α–CGRP–stimulated cAMP responses with an IC50 of 0.081 nM in human CGRP receptor-expressing HEK293 cells.
S8212 Olcegepant Olcegepant (BIBN4096; BIBN4096BS) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with an IC50 of 0.03 nM.
A2790 Eptinezumab (Anti-CALCA / CGRP) Eptinezumab (Anti-CALCA / CGRP) is a humanized monoclonal antibody that binds to calcitonin gene-related peptide (CGRP) and blocks its binding to the receptor. It is used in the preventive treatment of episodic migraine. MW: 143.36 kD.
A2791 Fremanezumab (Anti-CALCA / CGRP) Fremanezumab (Anti-CALCA / CGRP) is a humanized IgG2a monoclonal antibody that selectively and potently targets calcitonin gene-related peptide (CGRP). Fremanezumab has the potential for chronic migraine research.. MW: 145.5 kD.
A2790 Eptinezumab (Anti-CALCA / CGRP) Eptinezumab (Anti-CALCA / CGRP) is a humanized monoclonal antibody that binds to calcitonin gene-related peptide (CGRP) and blocks its binding to the receptor. It is used in the preventive treatment of episodic migraine. MW: 143.36 kD.
A2791 Fremanezumab (Anti-CALCA / CGRP) Fremanezumab (Anti-CALCA / CGRP) is a humanized IgG2a monoclonal antibody that selectively and potently targets calcitonin gene-related peptide (CGRP). Fremanezumab has the potential for chronic migraine research.. MW: 145.5 kD.
E1980New Atogepant Atogepant(MK-8031, AGN-241689) is a potent, selective, orally available antagonist of the calcitonin gene-related peptide (CGRP) receptor, with ki of 0.026 nM for human CGRP receptor. It is used for the preventive treatment episodic migraine.
E1824New Vazegepant hydrochloride Vazegepant hydrochloride (BHV-3500, Zavegepant), is a highly potent, selective, and structurally unique small molecule antagonist of CGRP receptor. It can also be used for the acute treatment of migraine.
S6659 Rimegepant (BMS-927711) Rimegepant (BMS-927711, BHV-3000) is a potent, selective, competitive human calcitonin gene-related peptide (CGRP) receptor antagonist with ki of 0.027 nM.
E1280 Ubrogepant Ubrogepant (MK-1602) is an antagonist of human calcitonin gene-related peptide receptor (CGRP). It potently blocks human α–CGRP–stimulated cAMP responses with an IC50 of 0.081 nM in human CGRP receptor-expressing HEK293 cells.
S8212 Olcegepant Olcegepant (BIBN4096; BIBN4096BS) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with an IC50 of 0.03 nM.
E1980New Atogepant Atogepant(MK-8031, AGN-241689) is a potent, selective, orally available antagonist of the calcitonin gene-related peptide (CGRP) receptor, with ki of 0.026 nM for human CGRP receptor. It is used for the preventive treatment episodic migraine.
E1824New Vazegepant hydrochloride Vazegepant hydrochloride (BHV-3500, Zavegepant), is a highly potent, selective, and structurally unique small molecule antagonist of CGRP receptor. It can also be used for the acute treatment of migraine.

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Tags: CGRP receptor antagonist | CGRP receptor inhibitor | CGRP receptor agonist