Home Biosimilar Antibodies Protein Tyrosine Kinase IGF-1R antibody Figitumumab (Anti-IGF1R / CD221) For research use only.
Not for use in humans.

Figitumumab (Anti-IGF1R / CD221)

Synonyms: CP-751871

Figitumumab (Anti-IGF1R / CD221) is a human monoclonal antibody directed against the insulin-like growth factor type I receptor (IGF1R) with potential antineoplastic activity. Figitumumab prevents IGF1 from binding to IGF1R with an IC50 of 1.8 nM. MW: 146.0 KD.

Figitumumab (Anti-IGF1R / CD221)

Purity & Quality Control

Choose Selective IGF-1R Inhibitors

Name Citation IGF-1R Insulin Receptor Others
Linsitinib (OSI-906) 191 IRR
NVP-AEW541 64 FLT3,Tek,FLT1
GSK1904529A 26
NVP-ADW742 22
BMS-536924 24 FAK,MEK,LCK
AG-1024 26
GSK1838705A 18 ALK
BMS-754807 51 TrkB,Met,TrkA
PQ 401 3
Picropodophyllin (PPP) 41
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Figitumumab (Anti-IGF1R / CD221) is a human monoclonal antibody directed against the insulin-like growth factor type I receptor (IGF1R) with potential antineoplastic activity. Figitumumab prevents IGF1 from binding to IGF1R with an IC50 of 1.8 nM. MW: 146.0 KD.

Product Details

CAS No. 943453-46-1
Molecular Weight 146
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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